Executive Functions and Conceptual Models: A First Look at a Complex Topic: Commentary

Background Since the late 19th century and over the last decades, executive functions (EF) have received increasing attentionin neuropsychology and clinical psychology for their influence on various domains of functioning, activities of daily living, and various psychological and mental disorders. Methods In this commentary, we aim to describe the major theoretical models of EF, their structures, clinical implications, with a focus on some neurodevelopmental disorders and major neurocognitive disorders. Results Two main approaches emerge: unitary models ( e.g. , Stuss and Benson, Norman and Shallice, Lezak) view EF as an integrated self-regulatory system, while multi-component models ( e.g ., Miyake, Diamond, Zelazo) describe separable but interconnected processes such as inhibition, working memory, and cognitive flexibility. In individuals with some neurodevelopmental disorders and major neurocognitive disorders, EF may be impaired (while sometimes only some EFs are affected, in other situations, all EFs are negatively influenced). Discussion Contemporary EF theoretical models integrate unitary and multi-component perspectives. They describe EF as coordinated yet distinguishable control processes. Looking at some clinical conditions, such as neurodevelopmental disorders and major neurocognitive disorders, both unitary and multi-component perspectives are supported: in some specific clinical conditions, specific processes and/or modules of EF may be selectively impaired. There is still an open debate on the role of EF as a transdiagnostic feature. Conclusion Executive functions represent a fundamental domain for understanding adaptive behaviour across the lifespan. Future research should further clarify the relationships among executive subcomponents, their neural mechanisms, and their role across psychological and neurological disorders, thereby contributing to more refined theoretical models and more targeted clinical assessment and rehabilitation strategies, as well as their role as a transdiagnostic construct.

Authors

Institutions

Publication Details

Journal
Clinical Practice and Epidemiology in Mental Health
Published
2026-09-11
DOI
https://doi.org/10.2174/0117450179462316260908052738
Primary Topic
Neural and Behavioral Psychology Studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
article

Executive Functions and Conceptual Models: A First Look at a Complex Topic: Commentary

Донателла Рита Петретто
Clinical Practice and Epidemiology in Mental Health
Neural and Behavioral Psychology Studies
article

Executive Functions and Conceptual Models: A First Look at a Complex Topic: Commentary

Донателла Рита Петретто
article en

Abstract

Background Since the late 19th century and over the last decades, executive functions (EF) have received increasing attentionin neuropsychology and clinical psychology for their influence on various domains of functioning, activities of daily living, and various psychological and mental disorders. Methods In this commentary, we aim to describe the major theoretical models of EF, their structures, clinical implications, with a focus on some neurodevelopmental disorders and major neurocognitive disorders. Results Two main approaches emerge: unitary models ( e.g. , Stuss and Benson, Norman and Shallice, Lezak) view EF as an integrated self-regulatory system, while multi-component models ( e.g ., Miyake, Diamond, Zelazo) describe separable but interconnected processes such as inhibition, working memory, and cognitive flexibility. In individuals with some neurodevelopmental disorders and major neurocognitive disorders, EF may be impaired (while sometimes only some EFs are affected, in other situations, all EFs are negatively influenced). Discussion Contemporary EF theoretical models integrate unitary and multi-component perspectives. They describe EF as coordinated yet distinguishable control processes. Looking at some clinical conditions, such as neurodevelopmental disorders and major neurocognitive disorders, both unitary and multi-component perspectives are supported: in some specific clinical conditions, specific processes and/or modules of EF may be selectively impaired. There is still an open debate on the role of EF as a transdiagnostic feature. Conclusion Executive functions represent a fundamental domain for understanding adaptive behaviour across the lifespan. Future research should further clarify the relationships among executive subcomponents, their neural mechanisms, and their role across psychological and neurological disorders, thereby contributing to more refined theoretical models and more targeted clinical assessment and rehabilitation strategies, as well as their role as a transdiagnostic construct.

Clinical Practice and Epidemiology in Mental HealthVol. 22(1)
University of Cagliari (IT)
Openalex Percentile: Top 9%
Neural and Behavioral Psychology Studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Executive Functions and Conceptual Models: A First Look at a Complex Topic: Commentary — Донателла Рита Петретто · Clinical Practice and Epidemiology in Mental Health (2026) | TGRS Research Map | TGRS