Incidental Thyroid Uptake on 18F-FES PET/CT Revealing Papillary Thyroid Carcinoma
A 70-year-old woman with endometrial carcinoma underwent 18F-FDG and 18F-FES PET/CT for pretreatment evaluation. Both studies demonstrated focal uptake in a nodule at the inferior pole of the left thyroid lobe. Ultrasonography revealed a TI-RADS 3 nodule, and fine-needle aspiration cytology showed atypia of undetermined significance. Total thyroidectomy was performed, and histopathology revealed a 20-mm noninvasive encapsulated classic papillary thyroid carcinoma. Estrogen receptor (ER) immunohistochemistry was unavailable; therefore, the relationship between 18F-FES uptake and ER expression could not be assessed. The patient subsequently received 100 mCi of radioactive iodine.
Authors
- Pınar Akkuş (ORCID: https://orcid.org/0000-0002-6336-3066)
- Asena Gökçay Canpolat (ORCID: https://orcid.org/0000-0003-1186-2960)
- Çiğdem Soydal (ORCID: https://orcid.org/0000-0002-6199-8551)
- Mahsun Cidemal
Institutions
- Ankara University (TR)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2026-09-11
- DOI
- https://doi.org/10.1097/rlu.0000000000006691
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00