Ultra-low-field portable MRI in neuroscience: Current status and future directions

INTRODUCTION: Modern medical imaging currently relies exclusively on high field magnetic resonance imaging (MRI) at high field (1.5 or 3 Tesla), which high purchase price, operational and maintenance costs represent major obstacles to access for about 90% of the world population. Recently, ultra-low field (100 mT or below) portable MRI (pMRI) systems have proven capable of producing images of adequate imaging quality within reasonable scan times, at significantly lower costs than standard systems. This article provides a review of currently operational pMRI systems that have applications in neuroimaging. MATERIALS AND METHODS: A narrative literature review on the use of portable MRI (pMRI) in neuroscience imaging was conducted in the PubMed database to identify studies published up to January 2026. RESULTS: Twenty-five articles were reviewed, 22 of which focused on pMRI in neuroimaging. Most studies highlighted feasibility and safety of bedside imaging in critically ill patients in order to circumvent the need for transport. Safe use in patients with ferromagnetic materials (including cardiac devices) and effectiveness in unsedated children have also been demonstrated. Diagnostic performance was evaluated in conditions such as stroke, multiple sclerosis and epilepsy. One study assessed feasibility in resource-limited settings. Home-based pMRI was explored in two studies, demonstrating potential for increased accessibility and urgent care. CONCLUSION: Solid evidence exits on the safety and clinical usefulness and performance of pMRI in neurological imaging. Although several clear advantages are demonstrated including safety, portability, accessibility and diagnostic capability, further research is needed to more clearly define a role for pMRI as a complement to or replacement for conventional high-field MRI.