Visible-Light-Promoted Phosphonylation Enabling the Use of Alkyl Thianthrenium Salts
Abstract A visible-light-promoted phosphonylation of alkyl thianthrenium salts with phosphonites is achieved through an EDA-complex-mediated radical generation, enabling C(sp3)–P(V) bond formation under photocatalyst-free, mild conditions. The reaction exhibits broad substrate scope and applicability to late-stage modification of complex molecules, providing a practical and sustainable protocol for the synthesis of alkyl phosphonates.
Authors
- Zhijun Zuo (ORCID: https://orcid.org/0000-0002-7838-4003)
- Ting Yuan (ORCID: https://orcid.org/0000-0002-0168-4075)
- Lu Bai (ORCID: https://orcid.org/0000-0002-7668-9524)
- Xinjun Luan (ORCID: https://orcid.org/0000-0002-5692-0936)
- Dongwei Zhao
- Ze Xu
- Jiayi Chen
Institutions
- Northwest University (US)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-09-11
- DOI
- https://doi.org/10.1021/acs.joc.6c01772
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Northwest University
- Key Research and Development Projects of Shaanxi Province