Intra-abdominal Versus Descending Thoracic Cannulation Techniques for Abdominal Normothermic Regional Perfusion.
Background: Abdominal normothermic regional perfusion (A-NRP) is postmortem perfusion of organs in the abdominal cavity and can be performed using multiple approaches, including femoral, intra-abdominal, and thoracic. Our program began with surgeons performing intra-abdominal cannulations with mechanical or balloon occlusion of the descending thoracic aorta for A-NRP procedures. Recently, we developed a novel technique using the descending thoracic aorta for arterial cannulation with right atrial venous drainage. Methods: All A-NRP cases performed by Regional Perfusion Services from July 1, 2024, to June 30, 2025, were retrospectively reviewed. Intraoperative parameters were collected for comparison. Results: < 0.001). The learning curves show a quicker descent in time and a lower nadir for the DT-NRP cases, indicating this technique may have a quicker learning curve and be a more efficient approach to cannulation. Conclusions: DT-NRP cannulation can be implemented for A-NRP with a quick learning curve, providing an additional cannulation option to the IA-NRP approach.
Authors
- Grace Marie Boyne
- Giuliano Testa (ORCID: https://orcid.org/0000-0001-9535-9961)
- Amar Gupta (ORCID: https://orcid.org/0000-0001-7186-1965)
- Jinyu Du (ORCID: https://orcid.org/0000-0002-7009-1986)
- Johanna Bayer (ORCID: https://orcid.org/0000-0003-3071-5755)
- Kara A. Monday
- Juan Sebastian Danobeitia (ORCID: https://orcid.org/0000-0003-1641-3822)
- Eric J. Martinez (ORCID: https://orcid.org/0000-0002-6930-0453)
- Scott Noesges
- Murphy Rayle (ORCID: https://orcid.org/0009-0006-7817-992X)
- Seung‐Hee Lee (ORCID: https://orcid.org/0000-0001-6958-6773)
- Olivia Walker
- Anji Wall
- Geoffrey Funk
Institutions
- Baylor University Medical Center (US)
- Baylor Scott & White Health (US)
- Southwest Transplant Alliance (US)
Publication Details
- Journal
- PubMed
- Published
- 2026-10-01
- DOI
- https://doi.org/10.1097/txd.0000000000002006
- Primary Topic
- Aortic Disease and Treatment Approaches
- Type
- article
- Field-Weighted Citation Impact
- 0.00