Fatal Infection with Dengue Virus and Avian Orthoavulavirus 1 in Traveler Returning from Saudi Arabia to France, 2025
A previously healthy 26-year-old man died of hemorrhagic fever with fulminant hepatitis and shock 36 hours after returning to France from Mecca, Saudi Arabia. Postmortem analyses detected low-level dengue virus RNA and positive NS1 antigen along with unexpected extremely high-titer disseminated velogenic avian orthoavulavirus 1 infection with elevated systemic cytokine responses.
Authors
- Darragh Duffy (ORCID: https://orcid.org/0000-0002-8875-2308)
- D Chopin
- Maud Salmona (ORCID: https://orcid.org/0000-0001-7985-6132)
- Olivier Schwartz (ORCID: https://orcid.org/0000-0002-0729-1475)
- Valérie Paradis (ORCID: https://orcid.org/0000-0003-3142-3762)
- Michael White (ORCID: https://orcid.org/0000-0002-7472-4138)
- Jean‐François Timsit (ORCID: https://orcid.org/0000-0002-6063-7383)
- Vincent Bondet (ORCID: https://orcid.org/0000-0002-6534-0984)
- Karine Lacombe (ORCID: https://orcid.org/0000-0001-8772-9029)
- Franck Verdonk (ORCID: https://orcid.org/0000-0001-7061-5594)
- François-Xavier Lescure (ORCID: https://orcid.org/0000-0002-2828-125X)
- Quentin Richier (ORCID: https://orcid.org/0000-0002-4962-6405)
- Lila Bouadma
- Marie Jaspard
- Jérôme Le Goff
- Quentin Le Hingrat
- Jamie Sugrue
- Salomé Schlupmann
- Morgane Mailhe
Institutions
- Inserm (FR)
- Université Paris Cité (FR)
- Sorbonne Université (FR)
- Hôpital Bichat-Claude-Bernard (FR)
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2026-09-11
- DOI
- https://doi.org/10.3201/eid3210.260736
- Primary Topic
- Mosquito-borne diseases and control
- Type
- article
- Field-Weighted Citation Impact
- 0.00