Cell Therapy Transplant Canada (CTTC) Consensus-Based Review for the Use of Supportive Care and Topical Therapies for Chronic Graft-Versus-Host Disease

This is a consensus-based Canadian review with the primary purpose of expanding knowledge regarding supportive and topical therapies for chronic graft vs. host disease (cGvHD). There is often a lack of confidence in treating certain organ specific manifestations, and access to specialists with organ specific expertise varies across the country. This paper covers information gained from a literature review and Canadian transplanter expertise and will serve as a guide for hematopoietic cell transplant healthcare providers to topical cGvHD therapies accessible in Canada. We will review common symptoms and signs focused specifically on skin, mouth, eye and genital tract cGvHD and on lifestyle modifications and topical treatments as an adjunct to our recent publication on systemic treatment for cGvHD.

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Publication Details

Journal
Current Oncology
Published
2026-09-10
DOI
https://doi.org/10.3390/curroncol33090548
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
Field-Weighted Citation Impact
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article

Cell Therapy Transplant Canada (CTTC) Consensus-Based Review for the Use of Supportive Care and Topical Therapies for Chronic Graft-Versus-Host Disease

Joseph Aziz, Gizelle Popradi, Kristjan Paulson, Mohamed Elemary et al.
Current Oncology
Hematopoietic Stem Cell Transplantation
article

Cell Therapy Transplant Canada (CTTC) Consensus-Based Review for the Use of Supportive Care and Topical Therapies for Chronic Graft-Versus-Host Disease

Joseph Aziz, Gizelle Popradi, Kristjan Paulson, Mohamed Elemary, Ram Vasudevan Nampoothiri, Kylie Lepic, Dennis Dong Hwan Kim, David Allan, Christopher Lemieux, Jennifer White, Kirk Schultz, Stephanie Maier
article en

Abstract

This is a consensus-based Canadian review with the primary purpose of expanding knowledge regarding supportive and topical therapies for chronic graft vs. host disease (cGvHD). There is often a lack of confidence in treating certain organ specific manifestations, and access to specialists with organ specific expertise varies across the country. This paper covers information gained from a literature review and Canadian transplanter expertise and will serve as a guide for hematopoietic cell transplant healthcare providers to topical cGvHD therapies accessible in Canada. We will review common symptoms and signs focused specifically on skin, mouth, eye and genital tract cGvHD and on lifestyle modifications and topical treatments as an adjunct to our recent publication on systemic treatment for cGvHD.

Current OncologyVol. 33(9)
BC Cancer Agency (CA), University Health Network (CA), University of British Columbia (CA), University of Ottawa (CA), University of Toronto (CA), Juravinski Cancer Centre (CA), Ottawa Hospital (CA), McGill University Health Centre (CA), Princess Margaret Cancer Centre (CA), Vancouver General Hospital (CA), University of Saskatchewan (CA), CancerCare Manitoba (CA), Saskatchewan Cancer Agency (CA), BC Children's Hospital (CA), Université Laval (CA), University of Manitoba (CA), McMaster University (CA)
Good health and well-being
Openalex Percentile: Top 10%
Hematopoietic Stem Cell Transplantation
DOIOpen Access PDFOpenAlex
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