ANTIBODY: An Immune-System Architecture for Long-Horizon AI Agent Oversight (Doctoral Research Proposal)

Long-horizon autonomous agents degrade in ways current oversight cannot catch, and the tools used to catch them are themselves degrading. This proposal investigates an external, model-agnostic oversight layer built on five principles drawn from immunology and reliability engineering: a dormant failure memory that activates only on derailment and grows more informative with runtime; predictive, hazard-based intervention in place of fixed-schedule context management; a sequential monitor whose statistical guarantees strengthen the longer it runs; oversight instruments that are cryptographically keyed so they cannot be learned away by future model generations; and a controlled cross-generation test of whether keyed instruments survive where fixed ones do not. The candidate holds twelve months of longitudinal, multi-vendor, long-horizon agentic production data suitable for the first-year hazard-modelling study without additional infrastructure. Deposited privately for timestamp/priority purposes ahead of doctoral-supervisor outreach. Full text is restricted; the title, abstract and publication date establish dated authorship.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-10
DOI
https://doi.org/10.5281/zenodo.22684602
Primary Topic
Artificial Immune Systems Applications
Type
article
Field-Weighted Citation Impact
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article

ANTIBODY: An Immune-System Architecture for Long-Horizon AI Agent Oversight (Doctoral Research Proposal)

Mohamed Alaya
Zenodo (CERN European Organization for Nuclear Research)
Artificial Immune Systems Applications
article

ANTIBODY: An Immune-System Architecture for Long-Horizon AI Agent Oversight (Doctoral Research Proposal)

Mohamed Alaya
article en

Abstract

Long-horizon autonomous agents degrade in ways current oversight cannot catch, and the tools used to catch them are themselves degrading. This proposal investigates an external, model-agnostic oversight layer built on five principles drawn from immunology and reliability engineering: a dormant failure memory that activates only on derailment and grows more informative with runtime; predictive, hazard-based intervention in place of fixed-schedule context management; a sequential monitor whose statistical guarantees strengthen the longer it runs; oversight instruments that are cryptographically keyed so they cannot be learned away by future model generations; and a controlled cross-generation test of whether keyed instruments survive where fixed ones do not. The candidate holds twelve months of longitudinal, multi-vendor, long-horizon agentic production data suitable for the first-year hazard-modelling study without additional infrastructure. Deposited privately for timestamp/priority purposes ahead of doctoral-supervisor outreach. Full text is restricted; the title, abstract and publication date establish dated authorship.

Zenodo (CERN European Organization for Nuclear Research)
University of Gabès (TN)
Industry, innovation and infrastructure
Openalex Percentile: Top 20%
Artificial Immune Systems Applications
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