Analytical dilemmas in assessing efficacy of radical cure of vivax malaria

The radical cure for Plasmodium vivax malaria involves administration of blood schizontocidal drug(s) against the acute attack and a hypnozoitocidal drug for the prevention of relapse due to latent hepatic stages of the parasite.1 There are many options for the former but just two for the latter: primaquine given daily for 7 or 14 days; or a single dose of tafenoquine. Currently the malaria control programme in India recommends 14 days of daily primaquine for radical cure of P. vivax.

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Publication Details

Journal
The Lancet Regional Health - Southeast Asia
Published
2026-09-10
DOI
https://doi.org/10.1016/j.lansea.2026.100867
Primary Topic
Malaria Research and Control
Type
article
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article

Analytical dilemmas in assessing efficacy of radical cure of vivax malaria

J Kevin Baird
The Lancet Regional Health - Southeast Asia
Malaria Research and Control
article

Analytical dilemmas in assessing efficacy of radical cure of vivax malaria

J Kevin Baird
article en

Abstract

The radical cure for Plasmodium vivax malaria involves administration of blood schizontocidal drug(s) against the acute attack and a hypnozoitocidal drug for the prevention of relapse due to latent hepatic stages of the parasite.1 There are many options for the former but just two for the latter: primaquine given daily for 7 or 14 days; or a single dose of tafenoquine. Currently the malaria control programme in India recommends 14 days of daily primaquine for radical cure of P. vivax.

The Lancet Regional Health - Southeast AsiaVol. 53
University of Indonesia (ID), University of Oxford (GB)
Good health and well-being
Openalex Percentile: Top 8%
Malaria Research and Control
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