Cefiderocol to Treat Multidrug-resistant Klebsiella pneumoniae Sepsis, Meningitis and Ventilator-associated Pneumonia in an Extremely Preterm Neonate
We report the case of an extremely preterm neonate (23 + 4 weeks, 486 g) whose mother had a history of multidrug-resistant infections during pregnancy, and who developed multidrug-resistant Klebsiella sepsis, meningitis and subsequent pneumonia. Cefiderocol was used to successfully treat the infections with no known adverse effects. The neonate was discharged home at 51 + 1 weeks.
Authors
- Shazia Masud (ORCID: https://orcid.org/0000-0001-9396-050X)
- J K Clayton
- Sriya Roychaudhuri (ORCID: https://orcid.org/0000-0003-0291-4175)
- Brandi Newby (ORCID: https://orcid.org/0000-0002-5123-5841)
Institutions
- University of British Columbia Hospital (CA)
- University of British Columbia (CA)
- Fraser Health (CA)
- Surrey Memorial Hospital (CA)
- Fairfax Neonatal Associates (US)
- B.C. Women's Hospital & Health Centre (CA)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2026-09-09
- DOI
- https://doi.org/10.1097/inf.0000000000005394
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00