A Rare Event Causing Blindness in an Unrecognised Pregnancy: A Case Report

Purtscher-like retinopathy (PLR) is a rare, non-traumatic microembolic angiopathy characteristically associated with systemic endothelial conditions, including pre-eclampsia.While PLR typically exhibits a self-limiting course with a highly favourable visual prognosis, severe cases result in permanent, treatmentrefractory blindness.We present a catastrophic, atypical case of bilateral PLR in an unrecognised pregnancy without any antenatal care.A 31-year-old primigravida without prior antenatal screening presented with a three-day history of sudden, bilateral central blurry vision and was newly diagnosed with severe preeclampsia.On presentation, her best-corrected visual acuity was 2/60 in the right eye and 3/60 in the left eye.Fundoscopy revealed prominent bilateral optic disc swelling, a complete macular star, and generalised Purtscher flecken.Optical coherence tomography confirmed severe macular oedema accompanied by serous macular detachment.Despite timely intervention with high-dose intravenous methylprednisolone, followed by a three-week tapering course of oral prednisolone, her visual acuity remained poor at the two-month follow-up, after which the patient defaulted.This case demonstrates that the co-existence of PLR with serous macular detachment represents an unusually severe tier of blood-retinal barrier breakdown.Furthermore, it highlights that a total lack of prenatal monitoring allows gestational hypertensive vasospasm to cascade, precipitating irreversible macular ischaemia that is entirely refractory to aggressive rescue corticosteroid therapy.

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Publication Details

Journal
Cureus
Published
2026-09-08
DOI
https://doi.org/10.7759/cureus.115976
Primary Topic
Retinal and Optic Conditions
Type
article
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article

A Rare Event Causing Blindness in an Unrecognised Pregnancy: A Case Report

Nor Syahira Shariffudin, Norshamsiah Md Din, Nurul Huda Md Amin, Fang Ying Lim
Cureus
Retinal and Optic Conditions
article

A Rare Event Causing Blindness in an Unrecognised Pregnancy: A Case Report

Nor Syahira Shariffudin, Norshamsiah Md Din, Nurul Huda Md Amin, Fang Ying Lim
article en

Abstract

Purtscher-like retinopathy (PLR) is a rare, non-traumatic microembolic angiopathy characteristically associated with systemic endothelial conditions, including pre-eclampsia.While PLR typically exhibits a self-limiting course with a highly favourable visual prognosis, severe cases result in permanent, treatmentrefractory blindness.We present a catastrophic, atypical case of bilateral PLR in an unrecognised pregnancy without any antenatal care.A 31-year-old primigravida without prior antenatal screening presented with a three-day history of sudden, bilateral central blurry vision and was newly diagnosed with severe preeclampsia.On presentation, her best-corrected visual acuity was 2/60 in the right eye and 3/60 in the left eye.Fundoscopy revealed prominent bilateral optic disc swelling, a complete macular star, and generalised Purtscher flecken.Optical coherence tomography confirmed severe macular oedema accompanied by serous macular detachment.Despite timely intervention with high-dose intravenous methylprednisolone, followed by a three-week tapering course of oral prednisolone, her visual acuity remained poor at the two-month follow-up, after which the patient defaulted.This case demonstrates that the co-existence of PLR with serous macular detachment represents an unusually severe tier of blood-retinal barrier breakdown.Furthermore, it highlights that a total lack of prenatal monitoring allows gestational hypertensive vasospasm to cascade, precipitating irreversible macular ischaemia that is entirely refractory to aggressive rescue corticosteroid therapy.

Cureus
Malacca General Hospital (MY)
Good health and well-being
Openalex Percentile: Top 8%
Retinal and Optic Conditions
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A Rare Event Causing Blindness in an Unrecognised Pregnancy: A Case Report — Nor Syahira Shariffudin, Norshamsiah Md Din, et al. · Cureus (2026) | TGRS Research Map | TGRS