Exploring the Anticancer Potential of Schiff Base Complexes: A Mini‐Review
Schiff bases are well known for their ability to form stable coordination compounds with several transition metals, making them valuable for medicinal chemistry purposes. These metal‐based compounds have attracted significant attention due to their enhanced biological activities, particularly their ability to act toward anticancer chemotherapy. This mini‐review provides a comprehensive overview of Schiff base complexes reported over the last 5 years, highlighting the recent advances related to their biological investigations. Cytotoxicity and interactions with biological targets have been detailed. The mechanisms underlying the capacity of these complexes to induce cell death in cancer cells are also described.
Authors
- Sabir Khan (ORCID: https://orcid.org/0000-0003-4557-238X)
- José Clayston Melo Pereira (ORCID: https://orcid.org/0000-0002-1647-5575)
- Marcos V. Palmeira‐Mello (ORCID: https://orcid.org/0000-0003-2550-5315)
- Atif Ahmad
- Anam (ORCID: https://orcid.org/0009-0006-3792-1163)
Institutions
- Universidade Federal de Pelotas (BR)
- Universidade Federal de São Carlos (BR)
- Universidade Estadual Paulista (Unesp) (BR)
Publication Details
- Journal
- ChemMedChem
- Published
- 2026-09-09
- DOI
- https://doi.org/10.1002/cmdc.70484
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00