Lipid lowering therapy in venous thromboembolism. A Clinical Consensus Statement of the ESC Working Group on Aorta and Peripheral Vascular Diseases, the ESC Working Group on Cardiovascular Pharmacotherapy, the ESC Working Group on Pulmonary Circulati
The aim of this clinical consensus statement of the European Society of Cardiology Working Group on Aorta and Peripheral Vascular Diseases, the Working Group on Cardiovascular Pharmacotherapy, the Working Group on Pulmonary Circulation & Right Ventricular Function, and the European Society of Vascular Medicine is to summarize existing evidence on lipid-lowering therapy (LLT) in primary and secondary prevention of venous thromboembolism (VTE). VTE, which comprises deep vein thrombosis (DVT) and pulmonary embolism (PE), shares common risk factors with atherosclerotic cardiovascular disease (ASCVD). While anticoagulation is the mainstay in the management of patients with VTE, it may be appropriate to define LLT as risk modifier in primary prevention of VTE in populations at high cardiovascular risk. In patients with VTE, assessment of cardiovascular risk factors, including lipid levels, is commonly part of routine cardiovascular care in accordance with existing ESC Guidelines. Finally, this clinical consensus statement highlights the gaps in evidence and the need for large-scale studies directly investigating the role of LLT in secondary prevention of recurrent VTE in high-risk populations.
Authors
- Mislav Vrsalović (ORCID: https://orcid.org/0000-0002-8432-404X)
- A. Bura-Rivière (ORCID: https://orcid.org/0000-0001-7469-2407)
- Oliver Schlager (ORCID: https://orcid.org/0000-0001-6934-5355)
- J. J. F. Belch (ORCID: https://orcid.org/0000-0001-8280-6689)
- Birgit Linnemann
- Lucia Mazzolai (ORCID: https://orcid.org/0000-0001-9650-3822)
- Victor Aboyans (ORCID: https://orcid.org/0000-0002-0322-9818)
- Christine Espinola–Klein (ORCID: https://orcid.org/0000-0001-9243-1761)
- Christian Heiß (ORCID: https://orcid.org/0000-0002-3212-8995)
- José F Rodriguez Palomares
- Heinz Drexel (ORCID: https://orcid.org/0000-0001-8191-9761)
- Frederikus A Klok
- Marianne Brodmann
- Thomas Gary
Institutions
- Universitat Autònoma de Barcelona (ES)
- University Hospital Centre Zagreb (HR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Johannes Gutenberg University Mainz (DE)
- Medical University of Graz (AT)
- Leiden University Medical Center (NL)
- Instituto de Salud Carlos III (ES)
- Ninewells Hospital (GB)
- University of Surrey (GB)
- Barmherzige Schwestern Krankenhaus Wien (AT)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Vall d'Hebron Institut de Recerca (ES)
- Centro de Investigación Biomédica en Red (ES)
- Sisters of Charity Hospital (HR)
- The Princess Grace Hospital (GB)
- Vall d'Hebron Hospital Universitari (ES)
- Vorarlberg Institute for Vascular Investigation and Treatment (AT)
- Medical University of Vienna (AT)
- University of Lausanne (CH)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2026-09-09
- DOI
- https://doi.org/10.1093/eurjpc/zwag481
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00