Mapping Cellular Senescence, Cellular Plasticity, and Alveolar Niche Heterogeneity in Human Lung Development

This repository contains the code, workflows, and source files used for the analyses presented in the manuscript. Contents Preprocessing and integration of pediatric lung snRNA-seq datasets Harmony integration and Azimuth annotation workflows Cell proportion analyses Differential gene expression analyses Gene ontology and pathway enrichment analyses Heatmap generation Feature plots and visualization scripts Pseudotime trajectory analyses Molecular clock and senescence-related analyses The repository is organized by figure to facilitate reproducibility and code availability.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-09
DOI
https://doi.org/10.5281/zenodo.22680989
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Mapping Cellular Senescence, Cellular Plasticity, and Alveolar Niche Heterogeneity in Human Lung Development

Gagandeep Kaur, Sadiya Shaikh, Irfan Rahman
Zenodo (CERN European Organization for Nuclear Research)
Telomeres, Telomerase, and Senescence
article

Mapping Cellular Senescence, Cellular Plasticity, and Alveolar Niche Heterogeneity in Human Lung Development

Gagandeep Kaur, Sadiya Shaikh, Irfan Rahman
article en

Abstract

This repository contains the code, workflows, and source files used for the analyses presented in the manuscript. Contents Preprocessing and integration of pediatric lung snRNA-seq datasets Harmony integration and Azimuth annotation workflows Cell proportion analyses Differential gene expression analyses Gene ontology and pathway enrichment analyses Heatmap generation Feature plots and visualization scripts Pseudotime trajectory analyses Molecular clock and senescence-related analyses The repository is organized by figure to facilitate reproducibility and code availability.

Zenodo (CERN European Organization for Nuclear Research)
University of Rochester (US)
Openalex Percentile: Top 11%
Telomeres, Telomerase, and Senescence
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