From Biological Insight to a New Class of Medicines for Hemophilia A
In this Perspective, the 2026 Lasker-DeBakey Clinical Medical Research Award winners describe the development of a bispecific antibody that mimics blood coagulation factor VIII, revolutionizing the treatment of hemophilia, a life-threatening bleeding disorder caused by lack of factor VIII.
Authors
- Tomoyuki Igawa (ORCID: https://orcid.org/0000-0003-0097-8220)
- Takehisa Kitazawa (ORCID: https://orcid.org/0000-0002-4958-7936)
- Kunihiro Hattori
Institutions
- Osaka Prefectural Toyonaka Support School (JP)
- Saitama International Medical Center (JP)
Publication Details
- Journal
- JAMA
- Published
- 2026-09-09
- DOI
- https://doi.org/10.1001/jama.2026.15612
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00