A Thermal-Frequency Locking Method for Permanent Magnet Magnetic Resonance Systems
Abstract Temperature-induced magnetic field drift is a dominant source of slow magnetic field variations in permanent magnet magnetic resonance (PMR) systems, resulting in line broadening, spectral distortion, and imaging artifacts. Conventional methods, such as field-frequency locking or software-based correction, require complicated additional hardware chains or suffer from limited performance. In this work, we propose a thermal-frequency locking (TFL) method to achieve long-term sub-ppm field stability. This method monitors the thermal state of the magnet array and employs a temperature–frequency prediction model to estimate the frequency drift caused by temperature-induced magnetic field variations. A corresponding compensation current is then applied through the Z0 coil to dynamically lock the resonance frequency. Experimental results show that under TFL, the maximum frequency drift over 72 h is reduced from approximately 1950 Hz to 12 Hz. From 12 to 72 h, the frequency drift is further constrained to 3 Hz, corresponding to an average drift rate of 2.3 ppb/h. In continuous ethanol monitoring, the worst-case peak frequency deviation decreases from 99.7 to 2.0 Hz, and the mean spectral correlation coefficient increases from 0.92 to 0.997. Moreover, restart-based shimming experiments demonstrate that the final line width decreases from 12.53 ± 0.96 Hz to 6.44 ± 0.33 Hz. These results confirm that the proposed TFL method effectively improves magnetic field stability, spectral reproducibility, and shimming robustness, providing a practical route for reliable long-term operation of compact PMR systems.
Authors
- Jian Zheng (ORCID: https://orcid.org/0000-0003-0616-5570)
- Yajie Xu (ORCID: https://orcid.org/0000-0002-6491-7390)
- Yu Peng (ORCID: https://orcid.org/0000-0001-8693-2113)
- Bowen Peng
- Ya Wang
- Jinyu Yang
Institutions
- University of Science and Technology of China (CN)
- Suzhou Institute of Biomedical Engineering and Technology (CN)
- Academy of Mathematics and Systems Science (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-09-10
- DOI
- https://doi.org/10.1021/acs.analchem.6c02978
- Primary Topic
- NMR spectroscopy and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Shandong Province