Neddylation E2 enzyme UBE2M inhibits inflammatory lung tumor microenvironment by blocking the cGAS-STING signal upon KrasG12D activation.

Authors

Xiufang Xiong (ORCID: https://orcid.org/0000-0001-6842-3673)
Danyi Zhai (ORCID: https://orcid.org/0000-0003-1766-3815)
C. F. Chen
Yawen Zheng (ORCID: https://orcid.org/0000-0002-9630-8194)
Xufan Li (ORCID: https://orcid.org/0000-0002-0775-3510)
Wenjing Lü (ORCID: https://orcid.org/0000-0001-5463-0946)
Yi Sun
Zhihua Chen (ORCID: https://orcid.org/0000-0002-4390-7636)
Mingjia Tan
Fengwu Zhang
Yongchao Zhao
Zhouyang Li (ORCID: https://orcid.org/0000-0002-7721-0175)
Pengyuan Liu
Hua Li
Yan Lu

Institutions

University of Michigan (US)
Sir Run Run Shaw Hospital (CN)
Women's Hospital, School of Medicine, Zhejiang University (CN)
Second Affiliated Hospital of Zhejiang University (CN)
First Affiliated Hospital Zhejiang University (CN)
Zhejiang University (CN)

Publication Details

Journal: PubMed
Published: 2026-09-30
DOI: https://doi.org/10.1016/j.scib.2026.08.050
Primary Topic: interferon and immune responses
Type: article
Field-Weighted Citation Impact: 0.00

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article

Neddylation E2 enzyme UBE2M inhibits inflammatory lung tumor microenvironment by blocking the cGAS-STING signal upon KrasG12D activation.

Xiufang Xiong, Danyi Zhai, C. F. Chen, Yawen Zheng et al.

Sep 30, 2026

PubMed

interferon and immune responses

article

Neddylation E2 enzyme UBE2M inhibits inflammatory lung tumor microenvironment by blocking the cGAS-STING signal upon KrasG12D activation.

Xiufang Xiong, Danyi Zhai, C. F. Chen, Yawen Zheng, Xufan Li, Wenjing Lü, Yi Sun, Zhihua Chen, Mingjia Tan, Fengwu Zhang, Yongchao Zhao, Zhouyang Li, Pengyuan Liu, Hua Li, Yan Lu

September 30, 2026article en

Abstract

No abstract available for this paper.

PubMedVol. 71(18)

University of Michigan (US), Sir Run Run Shaw Hospital (CN), Women's Hospital, School of Medicine, Zhejiang University (CN), Second Affiliated Hospital of Zhejiang University (CN), First Affiliated Hospital Zhejiang University (CN), Zhejiang University (CN)

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Openalex Percentile: Top 27%

interferon and immune responses

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