Sleep duration links to biological aging clocks: when sleep gets tough, aging gets going

In a recent large-scale study of biological ageing clocks published in Nature , the MULTI Consortium now shows sleep, often treated as a lifestyle habit, is a measurable sign of temporal biology. Their work suggests that deviations from optimal sleep duration are associated with accelerated biological aging across multiple organs and that healthy sleep may be one of the most practical and scalable ways for promoting longevity and reducing chronic disease risk. 1

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Publication Details

Journal
Signal Transduction and Targeted Therapy
Published
2026-09-07
DOI
https://doi.org/10.1038/s41392-026-02997-7
Primary Topic
Circadian rhythm and melatonin
Type
article
Field-Weighted Citation Impact
0.00

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article

Sleep duration links to biological aging clocks: when sleep gets tough, aging gets going

Melek C. Arkan, Despina Tawadros
Signal Transduction and Targeted Therapy
Circadian rhythm and melatonin
article

Sleep duration links to biological aging clocks: when sleep gets tough, aging gets going

Melek C. Arkan, Despina Tawadros
article en

Abstract

In a recent large-scale study of biological ageing clocks published in Nature , the MULTI Consortium now shows sleep, often treated as a lifestyle habit, is a measurable sign of temporal biology. Their work suggests that deviations from optimal sleep duration are associated with accelerated biological aging across multiple organs and that healthy sleep may be one of the most practical and scalable ways for promoting longevity and reducing chronic disease risk. 1

Signal Transduction and Targeted TherapyVol. 11(1)
Goethe University Frankfurt (DE), German Cancer Research Center (DE), Heidelberg University (DE), Georg Speyer Haus (DE), Frankfurt Cancer Institute (DE)
Deutsche Forschungsgemeinschaft, Hessisches Ministerium für Wissenschaft und Kunst
Good health and well-being
Openalex Percentile: Top 15%
Circadian rhythm and melatonin
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