Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

ABSTRACT The fundamental energy and latency limitations of the von Neumann architecture have necessitated a paradigm shift toward neuromorphic systems. This approach addresses the “memory wall” bottleneck by emulating the brain's event‐driven and massively parallel processing capabilities. However, the physical realization of these neurons in hardware remains a critical challenge. While complementary metal–oxide–semiconductor (CMOS) based implementations can simulate neuronal dynamics, they are constrained by high transistor counts and excessive power consumption, which limits their scalability for high‐density integration. This review provides a comprehensive analysis of artificial neurons starting with the description of biological neurons. The various neuron models and learning models are discussed to establish the functional requirements for hardware emulation. We subsequently detail the limitations of CMOS neurons as a motivation to the transition toward post‐CMOS neurons. These include emerging device‐based implementations of integrate‐and‐fire neurons, Hodgkin–Huxley neurons, and other neurons with novel functionalities. Furthermore, we discuss the pathway for enabling this brain‐inspired technology by evaluating system‐level architectures and deriving application‐specific requirements for real‐world deployment. Finally, we present conclusions and future outlooks for achieving energy‐efficient and high‐density neuromorphic computing systems.

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Publication Details

Journal
Advanced Functional Materials
Published
2026-09-07
DOI
https://doi.org/10.1002/adfm.77874
Primary Topic
Advanced Memory and Neural Computing
Type
article
Field-Weighted Citation Impact
0.00

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article

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Benoît H. Lessard, Kannan Udaya Mohanan, Ioannis Kymissis, Hocheon Yoo et al.
Advanced Functional Materials
Advanced Memory and Neural Computing
article

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Benoît H. Lessard, Kannan Udaya Mohanan, Ioannis Kymissis, Hocheon Yoo, Chang‐Hyun Kim
article en

Abstract

ABSTRACT The fundamental energy and latency limitations of the von Neumann architecture have necessitated a paradigm shift toward neuromorphic systems. This approach addresses the “memory wall” bottleneck by emulating the brain's event‐driven and massively parallel processing capabilities. However, the physical realization of these neurons in hardware remains a critical challenge. While complementary metal–oxide–semiconductor (CMOS) based implementations can simulate neuronal dynamics, they are constrained by high transistor counts and excessive power consumption, which limits their scalability for high‐density integration. This review provides a comprehensive analysis of artificial neurons starting with the description of biological neurons. The various neuron models and learning models are discussed to establish the functional requirements for hardware emulation. We subsequently detail the limitations of CMOS neurons as a motivation to the transition toward post‐CMOS neurons. These include emerging device‐based implementations of integrate‐and‐fire neurons, Hodgkin–Huxley neurons, and other neurons with novel functionalities. Furthermore, we discuss the pathway for enabling this brain‐inspired technology by evaluating system‐level architectures and deriving application‐specific requirements for real‐world deployment. Finally, we present conclusions and future outlooks for achieving energy‐efficient and high‐density neuromorphic computing systems.

Advanced Functional Materials
University of Ottawa (CA), Hanyang University (KR), Columbia University (US), Ottawa University (US)
University of Ottawa, Canada Foundation for Innovation, Natural Sciences and Engineering Research Council of Canada
Affordable and clean energy
Openalex Percentile: Top 20%
Advanced Memory and Neural Computing
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