Moulin’s Linear Atrophoderma: Two Case Reports and Literature Review

Jiaxin Meng, Lingzhu Liao, Shi Wu, Yong He, Yunfeng Hu, Saijun LiuDepartment of Dermatology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510632, People’s Republic of ChinaCorrespondence: Saijun Liu, Department of Dermatology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, 510632, People’s Republic of China, Email [email protected]: Moulin’s linear atrophoderma (LAM) is a rare acquired pigmentary atrophic dermatosis distributed along Blaschko’s lines, with an unclear etiology and poorly understood pathogenesis. This report presents two cases of LAM. Both patients were male, with onset during adolescence. Notably, one patient exhibited elevated antinuclear antibody (ANA) levels (1:320). Histopathological examination of both cases revealed a generally normal or mildly hyperplastic epidermis, hyperpigmentation of the basal layer, and a mixed inflammatory cell infiltrate (predominantly lymphocytes) in the dermis. Based on their clinical presentation and histopathological findings, both patients were diagnosed with LAM.Keywords: atrophic patch, Blaschko’s lines, linear atrophoderma of the skin