Deterministic Resolution of Multi-Scale Interface Singularities and Biomolecular Dynamics via ARC and V94-PhaseField Matter Generator

Large-scale biomolecular dynamics and multiphase fluid flows are bottlenecked by extreme timescale separations and spatial interface singularities. Stochastic trajectory integration fails due to multi-valley free energy barriers and VFT relaxation divergences. This paper presents a unified framework combining Advanced Rough Calculus (ARC) and the V94-PhaseField Matter Generator. ARC regularizes interface singularities into bounded polynomial operators, while ROA spectral collapse bypasses stochastic trajectory integration, enabling deterministic polynomial-time evaluation of multi-scale dynamics.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-09-06
DOI
https://doi.org/10.5281/zenodo.22427697
Primary Topic
Protein Structure and Dynamics
Type
preprint
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preprint

Deterministic Resolution of Multi-Scale Interface Singularities and Biomolecular Dynamics via ARC and V94-PhaseField Matter Generator

Seonggil Lee
Zenodo (CERN European Organization for Nuclear Research)
Protein Structure and Dynamics
preprint

Deterministic Resolution of Multi-Scale Interface Singularities and Biomolecular Dynamics via ARC and V94-PhaseField Matter Generator

Seonggil Lee
preprint en

Abstract

Large-scale biomolecular dynamics and multiphase fluid flows are bottlenecked by extreme timescale separations and spatial interface singularities. Stochastic trajectory integration fails due to multi-valley free energy barriers and VFT relaxation divergences. This paper presents a unified framework combining Advanced Rough Calculus (ARC) and the V94-PhaseField Matter Generator. ARC regularizes interface singularities into bounded polynomial operators, while ROA spectral collapse bypasses stochastic trajectory integration, enabling deterministic polynomial-time evaluation of multi-scale dynamics.

Zenodo (CERN European Organization for Nuclear Research)
Protein Structure and Dynamics
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