Targeting MCL-1 in cancer: promise, pitfalls, and the path forward

The current clinical trial evaluating the MCL-1 inhibitor (MCL-1i) S64315 represents an important step in translating preclinical findings into the clinic [1]. While MCL-1 inhibition showed strong ...

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Publication Details

Journal
Leukemia & lymphoma/Leukemia and lymphoma
Published
2026-09-06
DOI
https://doi.org/10.1080/10428194.2026.2723846
Primary Topic
Cell death mechanisms and regulation
Type
article
Field-Weighted Citation Impact
0.00

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article

Targeting MCL-1 in cancer: promise, pitfalls, and the path forward

Varsha Gandhi, Natalia Timofeeva, Aloke Sarkar
Leukemia & lymphoma/Leukemia and lymphoma
Cell death mechanisms and regulation
article

Targeting MCL-1 in cancer: promise, pitfalls, and the path forward

Varsha Gandhi, Natalia Timofeeva, Aloke Sarkar
article en

Abstract

The current clinical trial evaluating the MCL-1 inhibitor (MCL-1i) S64315 represents an important step in translating preclinical findings into the clinic [1]. While MCL-1 inhibition showed strong ...

Leukemia & lymphoma/Leukemia and lymphoma
The University of Texas MD Anderson Cancer Center (US)
CLL Global Research Foundation
Openalex Percentile: Top 18%
Cell death mechanisms and regulation
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