Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral phacoemulsification. No cardiorespiratory signs, which would suggest a more severe grade of reaction, were observed. The dog was treated successfully with chlorphenamine only and recovered uneventfully. Suggestions on reducing the risk of an anaphylactic reaction, current guidelines on anaphylaxis treatment, and previous reported reactions to NMBAs in dogs are discussed.

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Publication Details

Journal
Veterinary Record Case Reports
Published
2026-09-04
DOI
https://doi.org/10.1002/vrc2.70601
Primary Topic
Drug-Induced Adverse Reactions
Type
article
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article

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

Rob Ward, Kar Yee Phoon
Veterinary Record Case Reports
Drug-Induced Adverse Reactions
article

Cutaneous‐only hypersensitivity reaction presumed due to intravenous administration of atracurium in a dog

Rob Ward, Kar Yee Phoon
article en

Abstract

Summary There are limited case reports of hypersensitivity reactions to neuromuscular blocking agents (NMBAs) in veterinary species, and none describe cutaneous‐only signs. This case report describes a Grade 1 cutaneous‐only hypersensitivity reaction to atracurium in a 7‐year‐old dog undergoing general anaesthesia for cataract surgery with bilateral phacoemulsification. No cardiorespiratory signs, which would suggest a more severe grade of reaction, were observed. The dog was treated successfully with chlorphenamine only and recovered uneventfully. Suggestions on reducing the risk of an anaphylactic reaction, current guidelines on anaphylaxis treatment, and previous reported reactions to NMBAs in dogs are discussed.

Veterinary Record Case ReportsVol. 14(4)
University of Edinburgh (GB)
Openalex Percentile: Top 12%
Drug-Induced Adverse Reactions
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