Many labels, shared threat processes: classifying domain-labelled anxieties by mechanism rather than context

Abstract Psychology has accumulated numerous “X-anxieties” — math, test, foreign-language, public-speaking, driving, health and others — each with its own scale and specialist literature. Yet these experiences often share a phenomenological core of anticipatory worry, bodily arousal, catastrophic simulation and avoidance. This Review considers whether many such labels index context-bound expressions of common threat-regulation processes rather than independent mechanisms. A mechanism-first account is developed from experience to process to biological implementation: threat appraisal under uncertainty, interoceptive inference and attentional control are proposed as content-general operations through which diverse cues recruit a conserved defensive architecture. Human neuroimaging, psychophysiology and comparative evidence are broadly compatible with this account but do not establish mechanistic identity. In particular, non-significant cross-domain differences cannot demonstrate equivalence without formal equivalence testing or Bayesian evidence, and the diphasic autonomic response in blood–injection–injury phobia constitutes a genuine boundary case, suggesting that a shared appraisal core may feed more than one effector profile. The shared-process account is therefore treated as a parsimonious, falsifiable hypothesis. It generates predictions and boundary conditions for cross-context neural generalisation, autonomic equivalence, reliable cognitive transfer and latent structure, together with designs capable of distinguishing common processes from domain-specific mechanisms. Classifying anxieties by process rather than label could improve measurement, sharpen mechanistic tests and guide transdiagnostic interventions while avoiding premature reification of context-specific constructs.

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Publication Details

Journal
Psychoradiology
Published
2026-09-04
DOI
https://doi.org/10.1093/psyrad/kkag029
Primary Topic
Psychosomatic Disorders and Their Treatments
Type
article
Field-Weighted Citation Impact
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article

Many labels, shared threat processes: classifying domain-labelled anxieties by mechanism rather than context

Liye Zou, Steven Laureys, Peng Wang, Fred Paas
Psychoradiology
Psychosomatic Disorders and Their Treatments
article

Many labels, shared threat processes: classifying domain-labelled anxieties by mechanism rather than context

Liye Zou, Steven Laureys, Peng Wang, Fred Paas
article en

Abstract

Abstract Psychology has accumulated numerous “X-anxieties” — math, test, foreign-language, public-speaking, driving, health and others — each with its own scale and specialist literature. Yet these experiences often share a phenomenological core of anticipatory worry, bodily arousal, catastrophic simulation and avoidance. This Review considers whether many such labels index context-bound expressions of common threat-regulation processes rather than independent mechanisms. A mechanism-first account is developed from experience to process to biological implementation: threat appraisal under uncertainty, interoceptive inference and attentional control are proposed as content-general operations through which diverse cues recruit a conserved defensive architecture. Human neuroimaging, psychophysiology and comparative evidence are broadly compatible with this account but do not establish mechanistic identity. In particular, non-significant cross-domain differences cannot demonstrate equivalence without formal equivalence testing or Bayesian evidence, and the diphasic autonomic response in blood–injection–injury phobia constitutes a genuine boundary case, suggesting that a shared appraisal core may feed more than one effector profile. The shared-process account is therefore treated as a parsimonious, falsifiable hypothesis. It generates predictions and boundary conditions for cross-context neural generalisation, autonomic equivalence, reliable cognitive transfer and latent structure, together with designs capable of distinguishing common processes from domain-specific mechanisms. Classifying anxieties by process rather than label could improve measurement, sharpen mechanistic tests and guide transdiagnostic interventions while avoiding premature reification of context-specific constructs.

Psychoradiology
University of Liège (BE), Hangzhou Normal University (CN), South China Normal University (CN), UNSW Sydney (AU), Centre hospitalier de l'Université Laval (CA), Erasmus University Rotterdam (NL)
Quality Education
Openalex Percentile: Top 9%
Psychosomatic Disorders and Their Treatments
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