Direct clinician–pathologist multidisciplinary review and diagnostic revision in children with gastrointestinal disorders

Abstract Accurate pediatric gastrointestinal (GI) diagnosis often depends on integrating clinical, endoscopic, and histopathologic information. We evaluated the impact of weekly face‐to‐face multidisciplinary team (MDT) meetings on diagnosis in children undergoing endoscopy or liver biopsy at a tertiary center. This single‐center study included 53 patients discussed between March and November 2025; because 6 children were reviewed twice, the analysis was case‐based (59 MDT discussions). Diagnostic change was defined as any revision, reclassification, refinement, or exclusion of a suspected diagnosis after MDT review. Overall, diagnosis changed in 12 of 59 cases (20.3%). Endoscopic classifications changed significantly after MDT discussion ( p = 0.0091), as did histopathology classifications ( p = 0.0118). Pathologist experience was associated with pathology revision ( p = 0.0293), whereas patient‐specific parameters and endoscopist experience were not. Endoscopy requests to pathology were frequently sparse. These findings suggest that regular clinician–pathologist MDT review can improve diagnostic precision in pediatric GI practice.

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Publication Details

Journal
JPGN Reports
Published
2026-09-03
DOI
https://doi.org/10.1002/jpr3.70239
Primary Topic
Colorectal Cancer Screening and Detection
Type
article
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article

Direct clinician–pathologist multidisciplinary review and diagnostic revision in children with gastrointestinal disorders

Andreas Jenke, Christa Bergheim, Ralph Melchior, Irina Berger et al.
JPGN Reports
Colorectal Cancer Screening and Detection
article

Direct clinician–pathologist multidisciplinary review and diagnostic revision in children with gastrointestinal disorders

Andreas Jenke, Christa Bergheim, Ralph Melchior, Irina Berger, Emma Dahl
article en

Abstract

Abstract Accurate pediatric gastrointestinal (GI) diagnosis often depends on integrating clinical, endoscopic, and histopathologic information. We evaluated the impact of weekly face‐to‐face multidisciplinary team (MDT) meetings on diagnosis in children undergoing endoscopy or liver biopsy at a tertiary center. This single‐center study included 53 patients discussed between March and November 2025; because 6 children were reviewed twice, the analysis was case‐based (59 MDT discussions). Diagnostic change was defined as any revision, reclassification, refinement, or exclusion of a suspected diagnosis after MDT review. Overall, diagnosis changed in 12 of 59 cases (20.3%). Endoscopic classifications changed significantly after MDT discussion ( p = 0.0091), as did histopathology classifications ( p = 0.0118). Pathologist experience was associated with pathology revision ( p = 0.0293), whereas patient‐specific parameters and endoscopist experience were not. Endoscopy requests to pathology were frequently sparse. These findings suggest that regular clinician–pathologist MDT review can improve diagnostic precision in pediatric GI practice.

JPGN Reports
Witten/Herdecke University (DE), Klinikum Kassel (DE)
Reduced inequalities
Openalex Percentile: Top 13%
Colorectal Cancer Screening and Detection
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Direct clinician–pathologist multidisciplinary review and diagnostic revision in children with gastrointestinal disorders — Andreas Jenke, Christa Bergheim, et al. · JPGN Reports (2026) | TGRS Research Map | TGRS