Aneurysmal subarachnoid hemorrhage

Aneurysmal subarachnoid hemorrhage (SAH) is among the most critical acute cerebrovascular conditions, marked by high mortality rates, significant disability, and a considerable socio-economic burden. Women over 55 years of age, as well as individuals with arterial hypertension, hereditary predispositions, congenital vascular anomalies, and a history of smoking, are particularly susceptible. This article consolidates current data on the epidemiology, risk factors, pathogenesis, clinical presentation, and diagnosis of aneurysmal SAH. Special emphasis is placed on the mechanisms of early brain injury and delayed cerebral ischemia-two crucial factors influencing disease outcomes. Contemporary therapeutic strategies, including microsurgical clipping and endovascular embolization, are discussed in depth, addressing their indications, effectiveness, and associated risks. The significance of prompt diagnosis, specialized approaches, and patient management in neurovascular centers is highlighted. A systematic, multistage, and interdisciplinary strategy for managing patients with acute aneurysmal SAH is examined, demonstrating an approach that can enhance survival and improve functional outcomes while minimizing the risk of rebleeding and severe neurological deficits.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-09-04
DOI
https://doi.org/10.17116/jnevro202612608228
Primary Topic
Intracranial Aneurysms: Treatment and Complications
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article
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Aneurysmal subarachnoid hemorrhage

A.F. Yusupov, A. A. Yuldashev, F. А. Yusupov
S S Korsakov Journal of Neurology and Psychiatry
Intracranial Aneurysms: Treatment and Complications
article

Aneurysmal subarachnoid hemorrhage

A.F. Yusupov, A. A. Yuldashev, F. А. Yusupov
article en

Abstract

Aneurysmal subarachnoid hemorrhage (SAH) is among the most critical acute cerebrovascular conditions, marked by high mortality rates, significant disability, and a considerable socio-economic burden. Women over 55 years of age, as well as individuals with arterial hypertension, hereditary predispositions, congenital vascular anomalies, and a history of smoking, are particularly susceptible. This article consolidates current data on the epidemiology, risk factors, pathogenesis, clinical presentation, and diagnosis of aneurysmal SAH. Special emphasis is placed on the mechanisms of early brain injury and delayed cerebral ischemia-two crucial factors influencing disease outcomes. Contemporary therapeutic strategies, including microsurgical clipping and endovascular embolization, are discussed in depth, addressing their indications, effectiveness, and associated risks. The significance of prompt diagnosis, specialized approaches, and patient management in neurovascular centers is highlighted. A systematic, multistage, and interdisciplinary strategy for managing patients with acute aneurysmal SAH is examined, demonstrating an approach that can enhance survival and improve functional outcomes while minimizing the risk of rebleeding and severe neurological deficits.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(8)
Osh State University (KG)
Good health and well-being
Openalex Percentile: Top 11%
Intracranial Aneurysms: Treatment and Complications
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Aneurysmal subarachnoid hemorrhage — A.F. Yusupov, A. A. Yuldashev, et al. · S S Korsakov Journal of Neurology and Psychiatry (2026) | TGRS Research Map | TGRS