A Higher-Biotin Prenatal Multivitamin Formulation Improves Maternal and Cord Blood Biotin Biomarkers: A 24-Week Double-Blind, Randomized, Controlled Trial
= 0.044). In conclusion, a higher-biotin prenatal multivitamin formulation with biotin content exceeding the AI led to increases in biotin biomarkers in the mother-fetus dyad. The higher concentrations of biotin status biomarkers were related to mitigation of stress indicators. Further research is needed to confirm the positive role of a higher biotin intake in improving maternal and fetal health. This trial was registered on ClinicalTrials.gov (NCT05673070).
Authors
- Itamar Futterman (ORCID: https://orcid.org/0000-0002-6766-3437)
- Xinyin Jiang (ORCID: https://orcid.org/0000-0001-6090-371X)
- Fulvia Draicchio (ORCID: https://orcid.org/0000-0002-5686-3054)
- Marie A. Caudill (ORCID: https://orcid.org/0000-0002-7192-5743)
- Mastaneh Sharafi
- Olga Malysheva
- Isabelle Hanson
- Scott Chudnoff
- Adeline Grier-Welch (ORCID: https://orcid.org/0009-0007-0086-6655)
- Arianne Vance (ORCID: https://orcid.org/0009-0002-6544-4027)
- Nima Alamdari
Institutions
- The Graduate Center, CUNY (US)
- Maimonides Medical Center (US)
- City University of New York (US)
- Cornell University (US)
- Brooklyn College (US)
Publication Details
- Journal
- Journal of Dietary Supplements
- Published
- 2026-09-04
- DOI
- https://doi.org/10.1080/19390211.2026.2727024
- Primary Topic
- Biotin and Related Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00