Meta-CD: a metagenomic sequencing coverage and depth calculator for target species

epth Calculator (Meta-CD) is a convenient, biologist-friendly tool for determining coverage and depth to enhance taxonomic detection, functional profiling, and metagenome-assembled genome (MAG) recovery in metagenomics. It supports experimental design and post-sequencing analysis, modeling how genome size, relative abundance, sequencing depth, and DNA quantity influence detection of target species.

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Publication Details

Journal
Microbiology Resource Announcements
Published
2026-09-04
DOI
https://doi.org/10.1128/mra.00811-26
Primary Topic
Genomics and Phylogenetic Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Meta-CD: a metagenomic sequencing coverage and depth calculator for target species

Zhe Lyu, Callie Claiborne
Microbiology Resource Announcements
Genomics and Phylogenetic Studies
article

Meta-CD: a metagenomic sequencing coverage and depth calculator for target species

Zhe Lyu, Callie Claiborne
article en

Abstract

epth Calculator (Meta-CD) is a convenient, biologist-friendly tool for determining coverage and depth to enhance taxonomic detection, functional profiling, and metagenome-assembled genome (MAG) recovery in metagenomics. It supports experimental design and post-sequencing analysis, modeling how genome size, relative abundance, sequencing depth, and DNA quantity influence detection of target species.

Microbiology Resource Announcements
North Carolina State University (US)
U.S. Department of Agriculture, National Institute of Diabetes and Digestive and Kidney Diseases
Openalex Percentile: Top 18%
Genomics and Phylogenetic Studies
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