Discordant ¹⁸F-FDG and ⁶⁸Ga-DOTATATE PET/CT Findings Before Radionuclide Therapy in Small Cell Lung Cancer
A 54-year-old man with progressive small cell lung cancer underwent ¹⁸F-FDG and ⁶⁸Ga-DOTATATE PET/CT before radionuclide therapy. ¹⁸F-FDG PET/CT evaluated disease extent and identified metabolically active lesions. ⁶⁸Ga-DOTATATE PET/CT showed high SSTR expression in bone lesions and the pancreatic tail. Discordant hepatic uptake suggested tumor heterogeneity. The two scans provided complementary information on disease activity and therapeutic target expression, supporting patient selection and individualized planning for an SSTR-targeted radionuclide therapy-based comprehensive treatment strategy.
Authors
- Yanggang Liu
- 雷庆林
- Shijie Tang
- Ya Liu
- Lin Qiu
Institutions
- Target (United States) (US)
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Theranostics (New Zealand) (NZ)
- Molecular Theranostics (United States) (US)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2026-09-04
- DOI
- https://doi.org/10.1097/rlu.0000000000006656
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00