Paired comparison of extrinsic feedback effects on motor learning and functional recovery after stroke: a secondary analysis of randomized controlled trials

Introduction Extrinsic feedback (EF) provides external signals during motor practice to enhance knowledge of performance or results. While EF can improve outcomes after stroke, its relative effects on motor learning versus functional recovery remain unclear.Objective To directly compare EF effects on motor learning and functional recovery after stroke.Methods We conducted a secondary analysis of controlled trials from a previous systematic review, updated through November 2025. Trials reporting both motor learning and functional recovery were included. Standardized mean differences (SMDs) were calculated using random-effects meta-analysis. Multivariate meta-analysis accounted for within-study dependence, with analyses varying assumed correlations (ρ = 0.3, 0.5, 0.7). Risk of bias was assessed using ROB2, and certainty of the evidence with GRADE.Results Five trials (149 participants) were included. EF significantly improved motor learning (SMD 1.19; 95% CI 0.16–2.22; low-certainty). Effects on functional recovery were not significant (SMD 1.00; 95% CI −0.42–2.42; very low-certainty). Multivariate meta-analysis detected no statistical difference between outcomes (ΔSMD 0.19–0.23; p > 0.43).Conclusions No significant difference between outcomes, though uncertainty is substantial due to small sample size and imprecision. Motor learning gains may not generalize to functional recovery, supporting the value of assessing both outcomes in stroke rehabilitation trials.

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Publication Details

Journal
Disability and Rehabilitation
Published
2026-09-04
DOI
https://doi.org/10.1080/09638288.2026.2726997
Primary Topic
Stroke Rehabilitation and Recovery
Type
article
Field-Weighted Citation Impact
0.00

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article

Paired comparison of extrinsic feedback effects on motor learning and functional recovery after stroke: a secondary analysis of randomized controlled trials

Jakob Lorentzen, Ivana Bardino Novosel, Jan Christensen
Disability and Rehabilitation
Stroke Rehabilitation and Recovery
article

Paired comparison of extrinsic feedback effects on motor learning and functional recovery after stroke: a secondary analysis of randomized controlled trials

Jakob Lorentzen, Ivana Bardino Novosel, Jan Christensen
article en

Abstract

Introduction Extrinsic feedback (EF) provides external signals during motor practice to enhance knowledge of performance or results. While EF can improve outcomes after stroke, its relative effects on motor learning versus functional recovery remain unclear.Objective To directly compare EF effects on motor learning and functional recovery after stroke.Methods We conducted a secondary analysis of controlled trials from a previous systematic review, updated through November 2025. Trials reporting both motor learning and functional recovery were included. Standardized mean differences (SMDs) were calculated using random-effects meta-analysis. Multivariate meta-analysis accounted for within-study dependence, with analyses varying assumed correlations (ρ = 0.3, 0.5, 0.7). Risk of bias was assessed using ROB2, and certainty of the evidence with GRADE.Results Five trials (149 participants) were included. EF significantly improved motor learning (SMD 1.19; 95% CI 0.16–2.22; low-certainty). Effects on functional recovery were not significant (SMD 1.00; 95% CI −0.42–2.42; very low-certainty). Multivariate meta-analysis detected no statistical difference between outcomes (ΔSMD 0.19–0.23; p > 0.43).Conclusions No significant difference between outcomes, though uncertainty is substantial due to small sample size and imprecision. Motor learning gains may not generalize to functional recovery, supporting the value of assessing both outcomes in stroke rehabilitation trials.

Disability and Rehabilitation
Copenhagen University Hospital (DK), Rigshospitalet (DK)
Elsass Fonden, Ludvig og Sara Elsass Fond
Quality Education
Openalex Percentile: Top 14%
Stroke Rehabilitation and Recovery
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