Immediate Effects of Fascial Manipulation on Pain in Patients with Myofascial Densification and Central Sensitization: A Case Series

Background: The deep fascia is increasingly recognized as a potential source of pain, with densification manifesting as discomfort at myofascial points. Central sensitization (CS) significantly influences pain sensitivity, resulting in temporal, spatial, and threshold alterations in both acute and chronic pain conditions. Purpose: This case series investigates the immediate effects of fascial manipulation (FM) on pain at myofascial densified points (MDPs) and on clinical measures of CS. Methods: A total of 10 patients, aged 18-45 years, experiencing pain at MDPs were screened and selected based on specific criteria. Baseline measurements for the Visual Analog Scale (VAS) and the Central Sensitization Inventory (CSI) were collected. Densification points were identified and treated in a single session following the Stecco FM guidelines. Post-intervention values were recorded immediately after FM. Results: The study demonstrated a significant reduction in pain following FM (p ≤ 0.05). Mean VAS scores decreased from 07.33 ± 00.82 pre-intervention to 01.16 ± 01.17 post-intervention, while mean CSI scores decreased from 50.33 ± 07.65 to 30.00 ± 05.17. Conclusion: The findings of this case series suggest that FM may produce immediate reductions in pain in patients presenting with myofascial densification and features of CS.