MASLD and MASH: Steatotic liver disease joins the deadly quartet

Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to insulin resistance and cardiometabolic disorders. This review synthesizes current information on the epidemiology, pathophysiology, and treatment of MASLD and its progressive form, metabolic dysfunction- associated steatohepatitis (MASH), underscoring how to integrate established metabolic care with emerging treatments to address the growing MASLD burden.

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Publication Details

Journal
Cleveland Clinic Journal of Medicine
Published
2026-09-01
DOI
https://doi.org/10.3949/ccjm.93a.25117
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

MASLD and MASH: Steatotic liver disease joins the deadly quartet

Risheng Xu, N. Abate, Richard Su, Rise Stribling
Cleveland Clinic Journal of Medicine
Liver Disease Diagnosis and Treatment
article

MASLD and MASH: Steatotic liver disease joins the deadly quartet

Risheng Xu, N. Abate, Richard Su, Rise Stribling
article en

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD) is linked to insulin resistance and cardiometabolic disorders. This review synthesizes current information on the epidemiology, pathophysiology, and treatment of MASLD and its progressive form, metabolic dysfunction- associated steatohepatitis (MASH), underscoring how to integrate established metabolic care with emerging treatments to address the growing MASLD burden.

Cleveland Clinic Journal of MedicineVol. 93(9)
Baylor College of Medicine (US), TomoWave Laboratories (United States) (US)
Good health and well-being
Openalex Percentile: Top 10%
Liver Disease Diagnosis and Treatment
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