Seronegative Granulomatous Myositis With Bulbar Weakness and Reversible Cardiomyopathy: A Case Report

ABSTRACT A 64‐year‐old woman presented with seronegative idiopathic granulomatous myositis, featuring severe bulbar weakness, reversible cardiomyopathy (ejection fraction 20%–25%), hepatic injury, and acute kidney injury. Muscle biopsy confirmed granulomatous inflammation. Treatment with corticosteroids and intravenous immunoglobulin resulted in multi‐organ recovery, highlighting the importance of early immunosuppressive therapy.

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Publication Details

Journal
Clinical Case Reports
Published
2026-08-31
DOI
https://doi.org/10.1002/ccr3.73449
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
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article

Seronegative Granulomatous Myositis With Bulbar Weakness and Reversible Cardiomyopathy: A Case Report

John Ponugupati, Muhamed Abubacker, Balachandran Vaidyanathan
Clinical Case Reports
Inflammatory Myopathies and Dermatomyositis
article

Seronegative Granulomatous Myositis With Bulbar Weakness and Reversible Cardiomyopathy: A Case Report

John Ponugupati, Muhamed Abubacker, Balachandran Vaidyanathan
article en

Abstract

ABSTRACT A 64‐year‐old woman presented with seronegative idiopathic granulomatous myositis, featuring severe bulbar weakness, reversible cardiomyopathy (ejection fraction 20%–25%), hepatic injury, and acute kidney injury. Muscle biopsy confirmed granulomatous inflammation. Treatment with corticosteroids and intravenous immunoglobulin resulted in multi‐organ recovery, highlighting the importance of early immunosuppressive therapy.

Clinical Case ReportsVol. 14(9)
West Virginia University Hospitals (US)
Good health and well-being
Openalex Percentile: Top 10%
Inflammatory Myopathies and Dermatomyositis
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