When Myocardial Injury in Lupus Is Not Lupus: Probable Antimalarial‐Associated Cardiomyopathy Mimicking Lupus Myocarditis

ABSTRACT Antimalarial cardiotoxicity may mimic lupus myocarditis in systemic lupus erythematosus. We report a 53‐year‐old woman with chronic antimalarial exposure, myocardial injury, biventricular dysfunction, electrical abnormalities, low lupus activity, and no myocardial edema. Chloroquine withdrawal was followed by clinical improvement and left ventricular function recovery, supporting probable antimalarial‐associated cardiomyopathy.

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Journal
Clinical Case Reports
Published
2026-08-31
DOI
https://doi.org/10.1002/ccr3.73413
Primary Topic
Drug-Induced Ocular Toxicity
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article
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article

When Myocardial Injury in Lupus Is Not Lupus: Probable Antimalarial‐Associated Cardiomyopathy Mimicking Lupus Myocarditis

Alejandro Mariño, Cristian Orlando Porras Bueno, Ángel Alberto García Peña, Carlos Hernán Calderón Franco et al.
Clinical Case Reports
Drug-Induced Ocular Toxicity
article

When Myocardial Injury in Lupus Is Not Lupus: Probable Antimalarial‐Associated Cardiomyopathy Mimicking Lupus Myocarditis

Alejandro Mariño, Cristian Orlando Porras Bueno, Ángel Alberto García Peña, Carlos Hernán Calderón Franco, Laura Omaña-Álvarez, Diego Armando Pérez Covo, Emilio Jose Juan Juan-Guardela, Cáceres Méndez Edward Andres, Diego Alejandro Ortega Gómez, María Camila Bernal Beltrán
article en

Abstract

ABSTRACT Antimalarial cardiotoxicity may mimic lupus myocarditis in systemic lupus erythematosus. We report a 53‐year‐old woman with chronic antimalarial exposure, myocardial injury, biventricular dysfunction, electrical abnormalities, low lupus activity, and no myocardial edema. Chloroquine withdrawal was followed by clinical improvement and left ventricular function recovery, supporting probable antimalarial‐associated cardiomyopathy.

Clinical Case ReportsVol. 14(9)
Pontificia Universidad Javeriana (CO), Hospital Universitario San Ignacio (CO)
Good health and well-being
Openalex Percentile: Top 8%
Drug-Induced Ocular Toxicity
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When Myocardial Injury in Lupus Is Not Lupus: Probable Antimalarial‐Associated Cardiomyopathy Mimicking Lupus Myocarditis — Alejandro Mariño, Cristian Orlando Porras Bueno, et al. · Clinical Case Reports (2026) | TGRS Research Map | TGRS