Predicting intensive care needs in community-acquired pneumonia: clinical utility of the SMART-COP score in Southern India

Abstract Background Community-acquired pneumonia (CAP) presents a severe burden in developing regions, requiring precise triage. Traditional severity scores like CURB-65 often predict mortality rather than the immediate need for intensive care. The SMART-COP score proves to be a promising alternative for early triaging. Methods A prospective, longitudinal observational study was conducted among 123 adult CAP patients at a teaching hospital in Manipal, Karnataka, India. Clinical, laboratory, and radiological data were collected to calculate the SMART-COP score within 24 hours of admission. Primary evaluated outcomes included Intensive Respiratory or Vasopressor Support (IRVS) requirement, intensive care unit (ICU) length of stay, and in-hospital mortality. Results The cohort’s mean age was 61.33 ± 15.98 years. A significant majority (77.2%) needed ICU admission, with 58.5% requiring IRVS (56.9% intensive respiratory support, 24.4% inotropes). The in-hospital mortality rate was 14.6%, with mean admission SMART-COP score being 4.15 ± 2.61. SMART-COP significantly outperformed CURB-65 in predicting IRVS (AUROC 0.901 vs. 0.805; DeLong’s p = 0.007). Spearman’s correlation revealed a weak-to-moderate positive relationship between the admission score and ICU duration among admitted patients (rho = 0.315; p = 0.002). A count-based negative-binomial regression model demonstrated that every 1-point score increase was associated with a rate ratio of 1.34 for expected ICU days across the cohort. Multivariable regression confirmed that acute physiological instability independently drove the requirement for IRVS, superseding chronic comorbidities. Conclusion This single-centre validation study indicates that the SMART-COP score is a useful bedside triage instrument. Routine application at the primary care level may assist in early risk stratification and timely referral.

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Journal
npj Primary Care Respiratory Medicine
Published
2026-09-01
DOI
https://doi.org/10.1038/s41533-026-00555-w
Primary Topic
Pneumonia and Respiratory Infections
Type
article
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article

Predicting intensive care needs in community-acquired pneumonia: clinical utility of the SMART-COP score in Southern India

Nitin Bhat, Amitesh Pahari
npj Primary Care Respiratory Medicine
Pneumonia and Respiratory Infections
article

Predicting intensive care needs in community-acquired pneumonia: clinical utility of the SMART-COP score in Southern India

Nitin Bhat, Amitesh Pahari
article en

Abstract

Abstract Background Community-acquired pneumonia (CAP) presents a severe burden in developing regions, requiring precise triage. Traditional severity scores like CURB-65 often predict mortality rather than the immediate need for intensive care. The SMART-COP score proves to be a promising alternative for early triaging. Methods A prospective, longitudinal observational study was conducted among 123 adult CAP patients at a teaching hospital in Manipal, Karnataka, India. Clinical, laboratory, and radiological data were collected to calculate the SMART-COP score within 24 hours of admission. Primary evaluated outcomes included Intensive Respiratory or Vasopressor Support (IRVS) requirement, intensive care unit (ICU) length of stay, and in-hospital mortality. Results The cohort’s mean age was 61.33 ± 15.98 years. A significant majority (77.2%) needed ICU admission, with 58.5% requiring IRVS (56.9% intensive respiratory support, 24.4% inotropes). The in-hospital mortality rate was 14.6%, with mean admission SMART-COP score being 4.15 ± 2.61. SMART-COP significantly outperformed CURB-65 in predicting IRVS (AUROC 0.901 vs. 0.805; DeLong’s p = 0.007). Spearman’s correlation revealed a weak-to-moderate positive relationship between the admission score and ICU duration among admitted patients (rho = 0.315; p = 0.002). A count-based negative-binomial regression model demonstrated that every 1-point score increase was associated with a rate ratio of 1.34 for expected ICU days across the cohort. Multivariable regression confirmed that acute physiological instability independently drove the requirement for IRVS, superseding chronic comorbidities. Conclusion This single-centre validation study indicates that the SMART-COP score is a useful bedside triage instrument. Routine application at the primary care level may assist in early risk stratification and timely referral.

npj Primary Care Respiratory Medicine
Manipal Academy of Higher Education (IN), Kasturba Medical College, Manipal (IN)
Good health and well-being
Openalex Percentile: Top 10%
Pneumonia and Respiratory Infections
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