Important Residual Lesions and Early Unplanned Reinterventions After Pediatric Cardiac Surgery: A Scientific Statement From the American Heart Association

Optimal outcomes for congenital heart surgery depend on the expertise and judgment of an integrated multidisciplinary clinical team. The best outcomes require a comprehensive understanding of the patient's anatomy and physiology, an appropriate therapeutic plan, a meticulously executed operation that is technically optimal and facilitated by lesion-specific anesthesia and perfusion strategies, and skilled perioperative care. A principal factor contributing to adverse outcomes is the presence of important residual lesions after surgery, which may necessitate early unplanned cardiac reinterventions during the index hospitalization. Such reinterventions occur in ≈5% of all pediatric cardiac operations, with a higher incidence in younger patients and more complex procedures. The presence of significant residual lesions and the need for unplanned reinterventions are strongly associated with increased morbidity, mortality, and resource use. Wide center-level variation in the incidence and timing of unplanned reinterventions suggests an opportunity for quality improvement. In this scientific statement, we summarize the incidence, risk factors, and clinical outcomes of important residual lesions and early unplanned cardiac reinterventions. We review postoperative monitoring strategies and clinical indicators suggestive of a residual lesion, and we provide an overview of the noninvasive imaging modalities used for their identification and quantification. The roles of diagnostic and interventional cardiac catheterization in the management of residual lesions are discussed, along with surgical considerations for early reoperation. We highlight the importance of communication with patients and families. Last, key areas for future investigations are identified.

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Publication Details

Journal
Circulation
Published
2026-09-01
DOI
https://doi.org/10.1161/cir.0000000000001465
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Important Residual Lesions and Early Unplanned Reinterventions After Pediatric Cardiac Surgery: A Scientific Statement From the American Heart Association

Christine M. Riley, Kevin D. Hill, Cynthia K. Rigsby, Mjaye Mazwi et al.
Circulation
Congenital Heart Disease Studies
article

Important Residual Lesions and Early Unplanned Reinterventions After Pediatric Cardiac Surgery: A Scientific Statement From the American Heart Association

Christine M. Riley, Kevin D. Hill, Cynthia K. Rigsby, Mjaye Mazwi, Cesar E. Gonzalez De Alba, Emile Bacha, Meena Nathan, John M. Costello, Jane W. Newburger, Laura J. Olivieri
article en

Abstract

Optimal outcomes for congenital heart surgery depend on the expertise and judgment of an integrated multidisciplinary clinical team. The best outcomes require a comprehensive understanding of the patient's anatomy and physiology, an appropriate therapeutic plan, a meticulously executed operation that is technically optimal and facilitated by lesion-specific anesthesia and perfusion strategies, and skilled perioperative care. A principal factor contributing to adverse outcomes is the presence of important residual lesions after surgery, which may necessitate early unplanned cardiac reinterventions during the index hospitalization. Such reinterventions occur in ≈5% of all pediatric cardiac operations, with a higher incidence in younger patients and more complex procedures. The presence of significant residual lesions and the need for unplanned reinterventions are strongly associated with increased morbidity, mortality, and resource use. Wide center-level variation in the incidence and timing of unplanned reinterventions suggests an opportunity for quality improvement. In this scientific statement, we summarize the incidence, risk factors, and clinical outcomes of important residual lesions and early unplanned cardiac reinterventions. We review postoperative monitoring strategies and clinical indicators suggestive of a residual lesion, and we provide an overview of the noninvasive imaging modalities used for their identification and quantification. The roles of diagnostic and interventional cardiac catheterization in the management of residual lesions are discussed, along with surgical considerations for early reoperation. We highlight the importance of communication with patients and families. Last, key areas for future investigations are identified.

Circulation
Openalex Percentile: Top 10%
Congenital Heart Disease Studies
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