Focal nodular hyperplasia: a rare benign liver tumour in early childhood without predisposing factors

Focal nodular hyperplasia (FNH) is a rare benign hepatic lesion in children, particularly under 5 years of age. Most paediatric liver tumours in this age group are malignant, making an accurate diagnosis essential. We report a case of FNH involving the left hepatic lobe in a healthy child with no prior history of liver disease, chemotherapy or systemic illness. The child presented with a gradually enlarging abdominal mass and early satiety. Imaging with contrast-enhanced triple-phase CT demonstrated classical features of FNH, including arterial enhancement and a central scar. Due to the lesion's large size and associated symptoms, a left lateral segmentectomy was performed. Histopathology confirmed the diagnosis of FNH. Postoperative recovery was uneventful, and the patient remains well on long-term follow-up. This case highlights the diagnostic challenges of FNH in early childhood and the importance of considering benign hepatic lesions in the differential diagnosis of paediatric liver masses.

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Publication Details

Journal
BMJ Case Reports
Published
2026-09-01
DOI
https://doi.org/10.1136/bcr-2025-270129
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
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article

Focal nodular hyperplasia: a rare benign liver tumour in early childhood without predisposing factors

Nishant Agarwal, Tarun Kumar, Basant Kumar, Priya Mathew
BMJ Case Reports
Hepatocellular Carcinoma Treatment and Prognosis
article

Focal nodular hyperplasia: a rare benign liver tumour in early childhood without predisposing factors

Nishant Agarwal, Tarun Kumar, Basant Kumar, Priya Mathew
article en

Abstract

Focal nodular hyperplasia (FNH) is a rare benign hepatic lesion in children, particularly under 5 years of age. Most paediatric liver tumours in this age group are malignant, making an accurate diagnosis essential. We report a case of FNH involving the left hepatic lobe in a healthy child with no prior history of liver disease, chemotherapy or systemic illness. The child presented with a gradually enlarging abdominal mass and early satiety. Imaging with contrast-enhanced triple-phase CT demonstrated classical features of FNH, including arterial enhancement and a central scar. Due to the lesion's large size and associated symptoms, a left lateral segmentectomy was performed. Histopathology confirmed the diagnosis of FNH. Postoperative recovery was uneventful, and the patient remains well on long-term follow-up. This case highlights the diagnostic challenges of FNH in early childhood and the importance of considering benign hepatic lesions in the differential diagnosis of paediatric liver masses.

BMJ Case ReportsVol. 19(9)
Sanjay Gandhi Post Graduate Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 12%
Hepatocellular Carcinoma Treatment and Prognosis
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