Kechuanting Acupoint Sticking Therapy Alleviates Type 2 Airway Inflammation in Mice with Allergic Asthma by Modulating the Number of ILC2s
ILC2s and total ILC2s in the lungs and exacerbated type 2 airway inflammation. Conversely, intranasal BIBN-4096 decreased pulmonary ILC2s and mitigated type 2 airway inflammation. KAST reduces airway inflammation in allergic asthma, which is closely associated with downregulation of the CGRP/RAMP1 pathway and subsequent suppression of pulmonary ILC2s, as supported by pharmacologic inhibition.
Authors
- Meng Cao
- Wan Qi Shao
- Qiu Yue Zhao
- Shao Bo Guo
- Yi Lu
- Lan Ying Liu
- Yong Lin Chen
- Zhong Yi Wang
- Xiao Yan Gong
- Shu Mei Zhao
- Jing Jing Yang
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Visualized Experiments
- Published
- 2026-09-01
- DOI
- https://doi.org/10.3791/71749
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00