Kechuanting Acupoint Sticking Therapy Alleviates Type 2 Airway Inflammation in Mice with Allergic Asthma by Modulating the Number of ILC2s

ILC2s and total ILC2s in the lungs and exacerbated type 2 airway inflammation. Conversely, intranasal BIBN-4096 decreased pulmonary ILC2s and mitigated type 2 airway inflammation. KAST reduces airway inflammation in allergic asthma, which is closely associated with downregulation of the CGRP/RAMP1 pathway and subsequent suppression of pulmonary ILC2s, as supported by pharmacologic inhibition.

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Publication Details

Journal
Journal of Visualized Experiments
Published
2026-09-01
DOI
https://doi.org/10.3791/71749
Primary Topic
IL-33, ST2, and ILC Pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Kechuanting Acupoint Sticking Therapy Alleviates Type 2 Airway Inflammation in Mice with Allergic Asthma by Modulating the Number of ILC2s

Meng Cao, Wan Qi Shao, Qiu Yue Zhao, Shao Bo Guo et al.
Journal of Visualized Experiments
IL-33, ST2, and ILC Pathways
article

Kechuanting Acupoint Sticking Therapy Alleviates Type 2 Airway Inflammation in Mice with Allergic Asthma by Modulating the Number of ILC2s

Meng Cao, Wan Qi Shao, Qiu Yue Zhao, Shao Bo Guo, Yi Lu, Lan Ying Liu, Yong Lin Chen, Zhong Yi Wang, Xiao Yan Gong, Shu Mei Zhao, Jing Jing Yang
article en

Abstract

ILC2s and total ILC2s in the lungs and exacerbated type 2 airway inflammation. Conversely, intranasal BIBN-4096 decreased pulmonary ILC2s and mitigated type 2 airway inflammation. KAST reduces airway inflammation in allergic asthma, which is closely associated with downregulation of the CGRP/RAMP1 pathway and subsequent suppression of pulmonary ILC2s, as supported by pharmacologic inhibition.

Journal of Visualized Experiments(235)
Nanjing University of Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 17%
IL-33, ST2, and ILC Pathways
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