How do I distinguish celiac disease from other gluten- or wheat-related disorders in an adult patient?

How do I distinguish celiac disease from other glutenor wheat-related disorders in an adult patient? Q:Celiac disease, wheat allergy, and nonceliac gluten and wheat sensitivity are distinct gluten-and wheat-related disorders that share overlapping symptoms but require different diagnostic and management strategies (Table 1). 1 A systematic evaluation is essential to differentiate among them and guide appropriate care across clinical settings (Figure 1).

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Publication Details

Journal
Cleveland Clinic Journal of Medicine
Published
2026-09-01
DOI
https://doi.org/10.3949/ccjm.93a.25118
Primary Topic
Celiac Disease Research and Management
Type
article
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article

How do I distinguish celiac disease from other gluten- or wheat-related disorders in an adult patient?

Rishaan R. Sharma, Claire Jansson-Knodell, Alberto Rubio-Tapia
Cleveland Clinic Journal of Medicine
Celiac Disease Research and Management
article

How do I distinguish celiac disease from other gluten- or wheat-related disorders in an adult patient?

Rishaan R. Sharma, Claire Jansson-Knodell, Alberto Rubio-Tapia
article en

Abstract

How do I distinguish celiac disease from other glutenor wheat-related disorders in an adult patient? Q:Celiac disease, wheat allergy, and nonceliac gluten and wheat sensitivity are distinct gluten-and wheat-related disorders that share overlapping symptoms but require different diagnostic and management strategies (Table 1). 1 A systematic evaluation is essential to differentiate among them and guide appropriate care across clinical settings (Figure 1).

Cleveland Clinic Journal of MedicineVol. 93(9)
Cleveland Clinic (US), Cleveland Clinic Lerner College of Medicine (US)
Zero hunger
Openalex Percentile: Top 9%
Celiac Disease Research and Management
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