Pediatric outpatient parenteral antibiotic therapy: an important option for pediatric hospitals in Germany

Outpatient parenteral antibiotic therapy (OPAT) has been established for decades in children and adolescents with cystic fibrosis. Today, prolonged intravenous antibiotic treatment is less frequently required due to the increased use of oral sequential therapy with easily absorbable antibiotics. However, when it is needed in special situations, pediatric OPAT (pOPAT) can be a beneficial and safe alternative for various reasons (especially quality of life, limited inpatient resources, treatment costs). This article takes a critical look at the current status of OPAT in children and adolescents in Germany in order to foster the integration of pOPAT into the overall concept of pediatric infectiology.

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Publication Details

Journal
GMS. Hygiene and infection control
Published
2026-09-01
DOI
https://doi.org/10.3205/dgkh000670
Primary Topic
Antibiotics Pharmacokinetics and Efficacy
Type
article
Field-Weighted Citation Impact
0.00
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article

Pediatric outpatient parenteral antibiotic therapy: an important option for pediatric hospitals in Germany

Rachel Müller, Ulrich von Both, Arne Simon, Miriam Songa Stegemann et al.
GMS. Hygiene and infection control
Antibiotics Pharmacokinetics and Efficacy
article

Pediatric outpatient parenteral antibiotic therapy: an important option for pediatric hospitals in Germany

Rachel Müller, Ulrich von Both, Arne Simon, Miriam Songa Stegemann, Jennifer Neubert, Yeliz Akarsu, TeleKasper Project
article en

Abstract

Outpatient parenteral antibiotic therapy (OPAT) has been established for decades in children and adolescents with cystic fibrosis. Today, prolonged intravenous antibiotic treatment is less frequently required due to the increased use of oral sequential therapy with easily absorbable antibiotics. However, when it is needed in special situations, pediatric OPAT (pOPAT) can be a beneficial and safe alternative for various reasons (especially quality of life, limited inpatient resources, treatment costs). This article takes a critical look at the current status of OPAT in children and adolescents in Germany in order to foster the integration of pOPAT into the overall concept of pediatric infectiology.

GMS. Hygiene and infection control
LMU Klinikum (DE), Universitätskinderklinik (DE), Orthopädische Praxis (DE), Charité - Universitätsmedizin Berlin (DE), Ludwig-Maximilians-Universität München (DE), Saarland University (DE), Praxis (EE)
Openalex Percentile: Top 12%
Antibiotics Pharmacokinetics and Efficacy
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