Six decades of Taxol: From a Pacific Forest to a Life-Saving Drug
The journey of paclitaxel (Taxol®) represents a defining narrative in modern organic chemistry, reflecting the evolution of total synthesis, semisynthetic manufacturing and synthetic biology. The perspective highlights the achievements of researchers across disciplines to bring a molecule from a Pacific forest to becoming one of the most important life-saving drugs.
Authors
- S. Chandrasekhar (ORCID: https://orcid.org/0000-0003-3695-4343)
- Prathama S. Mainkar (ORCID: https://orcid.org/0000-0002-2696-3759)
- Malempati reddy Srimannarayana
Institutions
- Indian Institute of Chemical Technology (IN)
- GITAM University (IN)
Publication Details
- Journal
- Synlett
- Published
- 2026-08-31
- DOI
- https://doi.org/10.1055/a-2949-1878
- Primary Topic
- Cancer Treatment and Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 0.00