Native Spleen T1 Mapping for the Assessment of Hepatic Congestion in Children With Congenital Heart Disease

Background: Congestive hepatopathy in congenital heart disease (CHD) can lead to portal hypertension. Liver native T1 relaxation time (LT1) was reported to be associated with elevated central venous pressure and liver injury in CHD. This study investigated the utility of spleen native T1 relaxation time (ST1) in children with CHD, particularly those with Fontan circulation, and its association with hemodynamic parameters and biomarkers of liver injury.

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Publication Details

Journal
Circulation Reports
Published
2026-08-28
DOI
https://doi.org/10.1253/circrep.cr-25-0343
Primary Topic
Congenital Heart Disease Studies
Type
article
Field-Weighted Citation Impact
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article

Native Spleen T1 Mapping for the Assessment of Hepatic Congestion in Children With Congenital Heart Disease

Masaki Sato, Koichi Sagawa, Kenichiro Yamamura, Yuichi Ishikawa et al.
Circulation Reports
Congenital Heart Disease Studies
article

Native Spleen T1 Mapping for the Assessment of Hepatic Congestion in Children With Congenital Heart Disease

Masaki Sato, Koichi Sagawa, Kenichiro Yamamura, Yuichi Ishikawa, Katsuo Tao
article en

Abstract

Background: Congestive hepatopathy in congenital heart disease (CHD) can lead to portal hypertension. Liver native T1 relaxation time (LT1) was reported to be associated with elevated central venous pressure and liver injury in CHD. This study investigated the utility of spleen native T1 relaxation time (ST1) in children with CHD, particularly those with Fontan circulation, and its association with hemodynamic parameters and biomarkers of liver injury.

Circulation Reports
Kyushu University (JP), Kanazawa Medical University (JP), Fukuoka Children's Hospital and Medical Center for Infectious Diseases (JP), Mi Corporation (United States) (US)
Good health and well-being
Openalex Percentile: Top 10%
Congenital Heart Disease Studies
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