Quantitative OCT-Raman spectral imaging for intra-operative detection of positive margins in breast conserving surgery: a diagnostic accuracy study protocol

This record contains the completed SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 Checklist associated with the study protocol: "Quantitative OCT-Raman spectral imaging for intra-operative detection of positive margins in breast conserving surgery: a diagnostic accuracy study protocol." The checklist was completed to support transparent reporting of the study protocol and is provided in accordance with the SPIRIT 2013 reporting recommendations and F1000Research reporting guideline requirements. Protocol version: Version 1.0, 28 August 2026. Keywords: SPIRIT, reporting guideline, breast cancer, breast conserving surgery, Raman spectroscopy, optical coherence tomography, diagnostic accuracy study, protocol.