Modernizing the Taxonomy of Pediatric Cerebrovascular Disease
Understanding the pathophysiology associated with cerebrovascular disease has markedly improved, particularly because of advances in medical imaging, molecular biology, genetics, epidemiology, and information technology. However, integration of this new knowledge into nomenclature and classification of these conditions is lagging, leaving most of the terminology largely unchanged. The continued use of older names, often reliant on subjective descriptive features, can lead to confusion by inadvertently preserving outdated hypotheses and obscuring current understanding. Here, we outline the rationale and a proposed methodology to modernize the taxonomy of pediatric cerebrovascular disease, starting with moyamoya.
Authors
- Dulanka Silva
- Arastoo Vossough (ORCID: https://orcid.org/0000-0003-1346-427X)
- Corbett Wilkinson
- Prakash Muthusami (ORCID: https://orcid.org/0000-0002-7062-9571)
- Heather Fullerton
- Daniel Davila‐Williams
- Nomazulu Dlamini (ORCID: https://orcid.org/0000-0001-5927-3132)
- Sudhakar Vadivelu (ORCID: https://orcid.org/0000-0003-1419-5673)
- Vijeya Ganesan (ORCID: https://orcid.org/0000-0003-1864-6216)
- Rachel Pearson (ORCID: https://orcid.org/0000-0002-9418-8184)
- Edward R. Smith (ORCID: https://orcid.org/0000-0002-6317-8450)
- Michaela Waak (ORCID: https://orcid.org/0000-0002-8317-3331)
- Laura L. Lehman (ORCID: https://orcid.org/0000-0002-6007-0356)
- A See
- Marta Bertamino (ORCID: https://orcid.org/0000-0002-8096-7806)
- Bryan Philbrook
- Michael Dowling
- Sahar Hassanein
- Kristin Guilliams (ORCID: https://orcid.org/0000-0002-5518-3778)
- Darren Orbach
- Lisa Sun
- Samyami Chowdhury
- Lauren Beslow
- Janette Mailo (ORCID: https://orcid.org/0000-0002-3586-7080)
- Melissa Chung
- J. Michael Taylor
- Dana Harrar
- Namarata Shah
- Edward Yang
- Shivani Rangwala
- Aleksandra Minyeko
- Sarah Lee
- Siddharth Srivastava
- Manoelle Kossorotoff
- Moran Hausman-Kedem
- Christine Mrakotsky
- Adam Kundishora
- Gregory James
- Takahiro Ota
- Philipp Aldana
- Beverely Kienitz
- Paoloa Pergaimi
- Lisa Pabst
- Mubeen Rafay
- Leyila Kaseka
- Helena Marrell-Hesla
- Peter Dirks
Institutions
- Boston Children's Hospital (US)
- Hospital for Sick Children (CA)
- Boston Children's Museum (US)
Publication Details
- Journal
- Neurology Open Access
- Published
- 2026-08-28
- DOI
- https://doi.org/10.1212/wn9.0000000000000166
- Primary Topic
- Blood Coagulation and Thrombosis Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Seoul National University