N-formylmorpholine as green solvent promoted green synthesis of lactone derivatives

The reaction between dimethyl acetylenedicarboxylate and various OH-acids in N-formylmorpholine leads to butyrolactone derivatives in nearly good yields. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification and affordability of the catalyst.

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Publication Details

Journal: Iranian Journal of Organic Chemistry (IranJOC) شیمی آلی ایران
Published: 2026-08-28
DOI: https://doi.org/10.82361/1251455
Primary Topic: Multicomponent Synthesis of Heterocycles
Type: article
Field-Weighted Citation Impact: 0.00

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article

N-formylmorpholine as green solvent promoted green synthesis of lactone derivatives

IAU

Aug 28, 2026

Iranian Journal of Organic Chemistry (IranJOC) شیمی آلی ایران

Multicomponent Synthesis of Heterocycles

article

N-formylmorpholine as green solvent promoted green synthesis of lactone derivatives

IAU

August 28, 2026article en

Abstract

Iranian Journal of Organic Chemistry (IranJOC) شیمی آلی ایران

Industry, innovation and infrastructure

Openalex Percentile: Top 19%

Multicomponent Synthesis of Heterocycles

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N-formylmorpholine as green solvent promoted green synthesis of lactone derivatives — IAU · Iranian Journal of Organic Chemistry (IranJOC) شیمی آلی ایران (2026) | TGRS Research Map | TGRS