New persistent opioid use: a case for defining the problem

I congratulate Frangakis and colleagues on conducting the largest meta-analysis to date of new persistent opioid use (NPOU) after surgery in opioid-naïve patients.[1][1] However, I am concerned that the reported pooled incidence of 7.15% may be less informative than suggested because the meta-

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Publication Details

Journal
Regional Anesthesia & Pain Medicine
Published
2026-08-28
DOI
https://doi.org/10.1136/rapm-2026-108287
Primary Topic
Opioid Use Disorder Treatment
Type
article
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article

New persistent opioid use: a case for defining the problem

Duncan T. Ritchie
Regional Anesthesia & Pain Medicine
Opioid Use Disorder Treatment
article

New persistent opioid use: a case for defining the problem

Duncan T. Ritchie
article en

Abstract

I congratulate Frangakis and colleagues on conducting the largest meta-analysis to date of new persistent opioid use (NPOU) after surgery in opioid-naïve patients.[1][1] However, I am concerned that the reported pooled incidence of 7.15% may be less informative than suggested because the meta-

Regional Anesthesia & Pain Medicine
University of Aberdeen (GB), NHS Grampian (GB)
Openalex Percentile: Top 8%
Opioid Use Disorder Treatment
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New persistent opioid use: a case for defining the problem — Duncan T. Ritchie · Regional Anesthesia & Pain Medicine (2026) | TGRS Research Map | TGRS