Recognizing Strokes in the Post‐Anesthesia Care Unit in Adult Versus Pediatric Patients

BACKGROUND: Postoperative strokes can occur in adult and pediatric patients, with both ischemic and hemorrhagic etiologies. Unfortunately, it can be difficult to distinguish stroke symptoms from lingering anesthetic-related neurological effects. Even though there is currently no standardized screening tool, a systematic approach to symptomatic differentiation between anesthetic effects and stroke symptoms can help ensure early diagnosis of a stroke and thus minimize both morbidity and mortality. AIMS: This review aims to provide an overview of perioperative stroke in pediatric and adult patients, including epidemiology, clinical presentation, and risk factors, as well as an approach to differentiating suspected stroke from anesthetic-related neurological effects in the post-anesthesia care unit (PACU). DISCUSSION: In addition to symptomatology, stroke recognition in the PACU may be facilitated by incorporating consideration of the many perioperative stroke risk factors including surgery type, medications, and both modifiable and non-modifiable patient risk factors. While PACU strokes are rare, any delay in diagnosis and thus treatment can exacerbate adverse outcomes, so it remains important to maintain suspicion of stroke in patients with concerning symptoms and risk factors. CONCLUSIONS: This focused review discusses stroke etiology, its varying risk factors and symptomatology in pediatric and adult patients, and appropriate steps to take when confronted with concerning neurological symptoms in the PACU.

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Publication Details

Journal
Pediatric Anesthesia
Published
2026-08-28
DOI
https://doi.org/10.1002/pan.70280
Primary Topic
Blood Coagulation and Thrombosis Mechanisms
Type
article
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article

Recognizing Strokes in the Post‐Anesthesia Care Unit in Adult Versus Pediatric Patients

Codruta Soneru, Davit Kocharyan, Marius Birlea, Timothy R. Petersen et al.
Pediatric Anesthesia
Blood Coagulation and Thrombosis Mechanisms
article

Recognizing Strokes in the Post‐Anesthesia Care Unit in Adult Versus Pediatric Patients

Codruta Soneru, Davit Kocharyan, Marius Birlea, Timothy R. Petersen, Juliet Velhagen, Sagar Patel, Ricardo Falcon, Thomas Ferrer
article en

Abstract

BACKGROUND: Postoperative strokes can occur in adult and pediatric patients, with both ischemic and hemorrhagic etiologies. Unfortunately, it can be difficult to distinguish stroke symptoms from lingering anesthetic-related neurological effects. Even though there is currently no standardized screening tool, a systematic approach to symptomatic differentiation between anesthetic effects and stroke symptoms can help ensure early diagnosis of a stroke and thus minimize both morbidity and mortality. AIMS: This review aims to provide an overview of perioperative stroke in pediatric and adult patients, including epidemiology, clinical presentation, and risk factors, as well as an approach to differentiating suspected stroke from anesthetic-related neurological effects in the post-anesthesia care unit (PACU). DISCUSSION: In addition to symptomatology, stroke recognition in the PACU may be facilitated by incorporating consideration of the many perioperative stroke risk factors including surgery type, medications, and both modifiable and non-modifiable patient risk factors. While PACU strokes are rare, any delay in diagnosis and thus treatment can exacerbate adverse outcomes, so it remains important to maintain suspicion of stroke in patients with concerning symptoms and risk factors. CONCLUSIONS: This focused review discusses stroke etiology, its varying risk factors and symptomatology in pediatric and adult patients, and appropriate steps to take when confronted with concerning neurological symptoms in the PACU.

Pediatric Anesthesia
Charleston Area Medical Center (US), University of New Mexico (US), University of Colorado Anschutz Medical Campus (US), The University of Texas Southwestern Medical Center (US)
Good health and well-being
Openalex Percentile: Top 10%
Blood Coagulation and Thrombosis Mechanisms
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