Mini-ID – A minimally invasive drainage strategy for complicated skin and soft tissue infection

Rationale: Complicated skin and soft tissue infections (cSSTIs) are severe infections that may arise from abscesses, cellulitis, fasciitis, diabetic foot infections, trauma-related infections, and surgical site infections. Conventional treatment typically requires surgical drainage combined with systemic antibiotics. However, exploratory surgical drainage may cause tissue damage and increase inflammatory responses. Patient concerns: A 35-year-old male with diabetic ketoacidosis presented with progressive swelling, erythema, and pain in the right upper arm despite prior antibiotic therapy. Diagnosis: Complicated skin and soft tissue infection with localized abscess formation. Interventions: After the patient was stabilized and was treated using a minimally invasive sequential management strategy termed Mini-ID, which consists of minimal drainage, infection control, inflammation control, and adequate debridement. Drainage was performed using a skin biopsy punch instrument to minimize tissue damage. Culture-guided antibiotic therapy was subsequently administered. Outcomes: The patient demonstrated rapid clinical improvement with a significant reduction in inflammatory markers and complete wound healing at 3 months without requiring extensive surgical intervention. Lessons: The Mini-ID approach emphasizes that adequate source control rather than the extent of surgical incision may be sufficient in selected cSSTI cases. This strategy may reduce tissue injury and inflammatory burden while maintaining clinical effectiveness.

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Publication Details

Journal
Medicine
Published
2026-08-28
DOI
https://doi.org/10.1097/md.0000000000050275
Primary Topic
Orthopedic Infections and Treatments
Type
article
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article

Mini-ID – A minimally invasive drainage strategy for complicated skin and soft tissue infection

Patrick Szu-Ying Yen, Chao‐Wei Chang, Yun-Nan Lin, Hou-Yuen Tong
Medicine
Orthopedic Infections and Treatments
article

Mini-ID – A minimally invasive drainage strategy for complicated skin and soft tissue infection

Patrick Szu-Ying Yen, Chao‐Wei Chang, Yun-Nan Lin, Hou-Yuen Tong
article en

Abstract

Rationale: Complicated skin and soft tissue infections (cSSTIs) are severe infections that may arise from abscesses, cellulitis, fasciitis, diabetic foot infections, trauma-related infections, and surgical site infections. Conventional treatment typically requires surgical drainage combined with systemic antibiotics. However, exploratory surgical drainage may cause tissue damage and increase inflammatory responses. Patient concerns: A 35-year-old male with diabetic ketoacidosis presented with progressive swelling, erythema, and pain in the right upper arm despite prior antibiotic therapy. Diagnosis: Complicated skin and soft tissue infection with localized abscess formation. Interventions: After the patient was stabilized and was treated using a minimally invasive sequential management strategy termed Mini-ID, which consists of minimal drainage, infection control, inflammation control, and adequate debridement. Drainage was performed using a skin biopsy punch instrument to minimize tissue damage. Culture-guided antibiotic therapy was subsequently administered. Outcomes: The patient demonstrated rapid clinical improvement with a significant reduction in inflammatory markers and complete wound healing at 3 months without requiring extensive surgical intervention. Lessons: The Mini-ID approach emphasizes that adequate source control rather than the extent of surgical incision may be sufficient in selected cSSTI cases. This strategy may reduce tissue injury and inflammatory burden while maintaining clinical effectiveness.

MedicineVol. 105(35)
Kaohsiung Medical University (TW), Chang Gung University (TW), Kaohsiung Medical University Chung-Ho Memorial Hospital (TW), Chang Gung Memorial Hospital (TW), Regenerative Medicine Institute (MX)
Good health and well-being
Openalex Percentile: Top 8%
Orthopedic Infections and Treatments
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