Anaesthetic Management of CHARGE Syndrome with Anorectal Malformation in an Infant: A Case Report

CHARGE syndrome is a rare congenital disorder with multisystem involvement, posing significant anaesthetic challenges. We report the perioperative management of an 11-month-old male who was diagnosed with anorectal malformation and CHARGE syndrome and who underwent posterior sagittal anorectoplasty. Key anaesthetic considerations included craniofacial asymmetry, facial nerve palsy, and anticipated airway difficulties. Inhalational induction with careful preoxygenation, video laryngoscopy, and caudal analgesia facilitated safe anaesthesia. Post-operative airway compromise was managed with continuous positive airway pressure, and the patient recovered without further complications or intervention. Ultrasound guidance may facilitate identification of relevant anatomy and real-time visualization of injectate spread during caudal block. This case highlights the importance of meticulous pre-anaesthetic planning and multidisciplinary evaluation in children with CHARGE syndrome.

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Publication Details

Journal
Türk anesteziyoloji ve reanimasyon derneği dergisi
Published
2026-08-28
DOI
https://doi.org/10.4274/tjar.2026.262595
Primary Topic
Congenital Ear and Nasal Anomalies
Type
article
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article

Anaesthetic Management of CHARGE Syndrome with Anorectal Malformation in an Infant: A Case Report

Geeta Kamal, Nidhi Singh, Charu Charu
Türk anesteziyoloji ve reanimasyon derneği dergisi
Congenital Ear and Nasal Anomalies
article

Anaesthetic Management of CHARGE Syndrome with Anorectal Malformation in an Infant: A Case Report

Geeta Kamal, Nidhi Singh, Charu Charu
article en

Abstract

CHARGE syndrome is a rare congenital disorder with multisystem involvement, posing significant anaesthetic challenges. We report the perioperative management of an 11-month-old male who was diagnosed with anorectal malformation and CHARGE syndrome and who underwent posterior sagittal anorectoplasty. Key anaesthetic considerations included craniofacial asymmetry, facial nerve palsy, and anticipated airway difficulties. Inhalational induction with careful preoxygenation, video laryngoscopy, and caudal analgesia facilitated safe anaesthesia. Post-operative airway compromise was managed with continuous positive airway pressure, and the patient recovered without further complications or intervention. Ultrasound guidance may facilitate identification of relevant anatomy and real-time visualization of injectate spread during caudal block. This case highlights the importance of meticulous pre-anaesthetic planning and multidisciplinary evaluation in children with CHARGE syndrome.

Türk anesteziyoloji ve reanimasyon derneği dergisiVol. 54(4)
Chacha Nehru Bal Chikitsalaya (IN)
Zero hunger
Openalex Percentile: Top 11%
Congenital Ear and Nasal Anomalies
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