A Case Report of Horner’s Syndrome in Labour Neuroaxial Analgesia: Diagnosis, Management and Follow-Up

Background and Clinical Significance: Horner’s syndrome is an uncommon but recognised complication of neuroaxial analgesia in obstetric procedures, with an incidence of 0.4–4%. Case Presentation: This case report describes a 28-year-old primigravida who developed unilateral Horner’s syndrome approximately one hour after lumbar epidural analgesia placement for labour pain relief. Upon examination the patient presented with left-sided ptosis, anisocoria, and unexpected sensory blockade extending to the T3–T4 level, accompanied by localised numbness in the left breast and transient upper limb paraesthesia. The pathophysiology of Horner’s syndrome involves cephalad spread of local anaesthetic toward the superior cervical sympathetic chain, disrupting sympathetic innervation to the ocular and facial areas. Primary and secondary damage to the sympathetic pathways in the central nervous offer a wide differential diagnosis. The management was conservative, including reduction in epidural bolus infusion rates and careful monitoring. The patient experienced complete resolution of all symptoms within five hours and delivered vaginally without complications. Conclusions: This case demonstrates the characteristically benign and self-limited nature of this complication, emphasising the importance of clinical awareness, proper reassurance of patients, and avoidance of unnecessary diagnostic testing.

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Publication Details

Journal
Reports — Medical Cases Images and Videos
Published
2026-08-28
DOI
https://doi.org/10.3390/reports9030289
Primary Topic
Sympathectomy and Hyperhidrosis Treatments
Type
article
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article

A Case Report of Horner’s Syndrome in Labour Neuroaxial Analgesia: Diagnosis, Management and Follow-Up

Marie‐Joe Dib, Corinne Grandjean, Mariana Fernandes, Ouanes Amine Ben Saad et al.
Reports — Medical Cases Images and Videos
Sympathectomy and Hyperhidrosis Treatments
article

A Case Report of Horner’s Syndrome in Labour Neuroaxial Analgesia: Diagnosis, Management and Follow-Up

Marie‐Joe Dib, Corinne Grandjean, Mariana Fernandes, Ouanes Amine Ben Saad, Yong-Shun Thoo
article en

Abstract

Background and Clinical Significance: Horner’s syndrome is an uncommon but recognised complication of neuroaxial analgesia in obstetric procedures, with an incidence of 0.4–4%. Case Presentation: This case report describes a 28-year-old primigravida who developed unilateral Horner’s syndrome approximately one hour after lumbar epidural analgesia placement for labour pain relief. Upon examination the patient presented with left-sided ptosis, anisocoria, and unexpected sensory blockade extending to the T3–T4 level, accompanied by localised numbness in the left breast and transient upper limb paraesthesia. The pathophysiology of Horner’s syndrome involves cephalad spread of local anaesthetic toward the superior cervical sympathetic chain, disrupting sympathetic innervation to the ocular and facial areas. Primary and secondary damage to the sympathetic pathways in the central nervous offer a wide differential diagnosis. The management was conservative, including reduction in epidural bolus infusion rates and careful monitoring. The patient experienced complete resolution of all symptoms within five hours and delivered vaginally without complications. Conclusions: This case demonstrates the characteristically benign and self-limited nature of this complication, emphasising the importance of clinical awareness, proper reassurance of patients, and avoidance of unnecessary diagnostic testing.

Reports — Medical Cases Images and VideosVol. 9(3)
University of Fribourg (CH), Centre Hospitalier Universitaire Vaudois (CH), Fribourg Development Agency (CH), University Hospital of Geneva (CH), Hôpital Orthopédique de la Suisse Romande (CH)
Decent work and economic growth
Openalex Percentile: Top 10%
Sympathectomy and Hyperhidrosis Treatments
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A Case Report of Horner’s Syndrome in Labour Neuroaxial Analgesia: Diagnosis, Management and Follow-Up — Marie‐Joe Dib, Corinne Grandjean, et al. · Reports — Medical Cases Images and Videos (2026) | TGRS Research Map | TGRS